Spironolactone did, however, show an improvement in rates of HF hospitalizations
Whether there is a subset of patients with heart failure with preserved ejection fraction (HFpEF) that benefit from spironolactone therapy is unclear
A total of 457 patients had HFmrEF
Spironolactone in Patients With an Echocardiographic HFpEF Phenotype Suggestive of Cardiac Amyloidosis: Results From TOPCAT Free Access Clinical