Call your doctor for medical advice about side effects
In the pediatric population, patients are commonly induced before caudal placement
Cardiovascular/Circulatory
The optimal dose of clonidine is largely unknown; in one study, caudal clonidine 3 μg kg −1 resulted in a zero incidence of emergence agitation, but at this dose haemodynamic
175%
2 mg kg −1 h −1 for infants and neonates, 0
2% and clonidine two microgram per kilogram (mcg/kg) on the incidence of EA, with respiratory
Clonidine is an antihypertensive drug that lowers blood pressure and heart rate by relaxing the arteries and increasing the blood supply to the heart; it has other FDA-approved indications such as
1 mg/12 hr) Drug class: Antiadrenergic agents, centrally acting
Clonidine produces a local anesthetic sparing effect with a dose-dependent decrease in levobupivacaine MLAC for caudal anesthesia
The major side-effects of concern were bradycardia, hypotension, respiratory depression and urinary retention
2%) are the most commonly used local anesthetic blocks for single-shot caudal blocks
When combined with a local anesthetic in an epidural solution, both clonidine and dexmedetomidine will decrease the time of onset of the
It is concluded that small doses of intrathecal clonidine significantly prolong the anesthetic and analgesic effects of bupivacaine in a dose-dependent manner and that 150 &mgr;g ofClonidine seems to be the preferred dose, in terms of effect versus unwarranted side effects, when prolongation of spinal anesthesia is desired
25% bupivacaine with 1-2 micro g/kg clonidine improves the duration and quality of analgesia provided by caudal block, although results differ widely, ranging from 16
Single-dose caudal local anesthetic has a limited duration, which may be insufficient for long surgery
Figure 1
(15) with clonidine/bupivacaine
25% levobupivacaine for caudal analgesia significantly prolonged the duration of analgesia, without any side effect
Caudal epidural block with bupivacaine is one of the most For caudal blockade, the addition of dexmedetomidine and clonidine have an equipotent effect on the characteristics of the block, and they may be the drugs of choice to prolong duration of caUDal anesthesia provided by a single injection in children
have compared single-dose caudal morphine 50 μg/kg, clonidine 2 μg/kg, and hydromorphone 10 μg/kg and have found that morphine provides more sustained initial analgesia, though with a higher incidence of postoperative nausea/vomiting
Pastureau F, Lebrun T, et al: Caudal clonidine for postoperative analgesia in adults
More than 60% of children undergoing orchidopexy with this If you take it twice a day, take the first dose in the morning and the second dose in the evening
The increased risk of hypotension, fainting, and sedation may limit its usefulness