Various forms of ONJ have been described since
Alendronate belongs to the class of bisphosphonate medications and is used to treat osteoporosis and other bone-related conditions
Although osteoporotic patients received doses one-tenth
Bisphosphonate-related osteonecrosis of the jaws (BRONJ) was the term given by American Association of Oral and Maxillofacial Surgeons []
Like other bisphosphonates, it inhibits bone resorption
In the alendronate treatment group, 442 patients had osteonecrosis of the femoral head
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) can be spontaneous, commonly appearing in the mylohyoid ridge area
However, it’s also possible to experience severe bone pain from taking Fosamax
Patients should be advised to report any ear pain, discharge from ear or an ear infection during treatment with a bisphosphonate
Bisphosphonate therapy has made a significant impact in the palliation of cancer morbidity
The underlying etiology is unclear and may be multifactorial
Bisphosphonates are synthetic analogs of pyrophosphate that bind to the hydroxyapatite found in bone
Bisphosphonate
Long-term use of medications to increase bone density might contribute to developing osteonecrosis of the jaw