Although the mechanisms of action of ondansetron in treating postoperative nausea and vomiting and cytotoxic induced nausea and vomiting may
Generic name: ondansetron hydrochloride Dosage form: tablet Drug class: 5HT3 receptor antagonists Medically reviewed by Drugs
While its mechanism of action has not been fully characterized
Mechanism of Action
Subsequently, the availability of labelled 5-HT3 receptor ligands allowed identification of 5-HT3 Ondansetron
1 Mechanism of Action
It is in the short-acting insulin class of drugs
Mechanism not fully characterized; selective 5-HT3 receptor antagonist; binds to 5-HT3 receptors both in periphery and in CNS, with primary effects in GI tract
Ondansetron is a selective 5-HT 3 receptor antagonist
[15], [16] Figure 7
Ondansetron is a serotonin-3 (5-hydroxytryptamine-3, 5-HT 3) receptor antagonist, have been shown to have a good antiemetic effect in patients receiving chemotherapy and in situations with vomiting after surgery 1)
Review paper: selectivity of 5-HT3 receptor antagonists and anti-emetic mechanisms of action
Metoclopramide and antihistamines are first-line options for nausea and vomiting in pregnancy The mechanisms of action of antiemetics, such as antagonising neurotransmitters
Serotonin receptors of the 5-HT3 type are present both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger
F
Ondansetron tablets, USP 8 mg (ondansetron hydrochloride, USP equivalent to 8 mg of ondansetron), are yellow, oval, film-coated tablets, debossed with "8" on one side and "NO" on the other
15 mg/kg of ondansetron had no effect on esophageal motility, gastric motility, lower esophageal sphincter pressure, or small
Promethazine also has off-label uses for nausea and vomiting in pregnancy