Some people will have more side effects than others, while others don't experience any side effects at all
Having few or no side effects does not mean the drug is not effective
Tamoxifen and raloxifene are the only drugs approved in the US to help lower the risk of breast cancer, although for some women, other drugs called aromatase inhibitors Tamoxifen is used to treat breast cancer that has spread to other parts of the body in men and women
It's a treatment for: early breast cancer
FDA-approved Indications include treatment of breast cancer in both females and males, adjuvant treatment of breast cancer after patients have completed their primary Irregular menstrual cycles or spotting
When comparing these side effects in women randomised to low-dose (2
It can also lower the risk of developing breast cancer
mood changes
Adult dosage (ages 18 years and older) The typical recommended dosage is 20-40 mg per day taken in one or divided doses for 5 Some may stop because of common side effects, such as hot flashes, vaginal dryness and mood swings
Role of endocrine responsiveness and adjuvant therapy in very young women (below 35 years) with operable breast cancer and node negative disease
The drug can reduce incidence of breast cancer in high-risk individuals, but side effects that mimic menopause have led to low rates of uptake
Hot flashes and night sweats
That's what my oncologist said he will put me on once I'm done on my treatment
Neuropathy
1016/S0007-4551 (20)30046-1
Hormone therapy (side effects of tamoxifen, aromatase inhibitors and ovarian suppression) Learn about possible long-term side effects
For other women, side effects are quite tolerable
Tamoxifen is available as an oral tablet and as an oral Depending on a woman's menopausal status, tamoxifen can have different effects on the bones
In this retrospective study, we sought to establish the role of toremifene as an endocrine therapy for premenopausal patients with estrogen and In a selected group of 35 young women less than 35 years of age with a first Compared with women receiving tamoxifen, women with a bmi of 25 kg et al
1038/sj Expect side effects
Women taking tamoxifen should report any abnormal vaginal discharge, vaginal bleeding, menstrual irregularities, or pain or pressure in the lower belly (abdomen) to Tamoxifen is generally well tolerated in older patients and is extremely low in cost and readily available
Less common but serious side effects of hormone therapy drugs are listed below
The breast cancer medication most commonly identified with ocular side effects is tamoxifen
The first endocrine therapy was surgical oophorectomy in young women with randomised postmenopausal women to tamoxifen or anastrozole for 5 years
The researchers looked at the results from women treated with tamoxifen alone, with tamoxifen plus ovarian suppression, and with exemestane plus Another aspect of patient perceptions about tamoxifen identified in our study was the concern about side effects
Some side effects may occur that usually do not need medical attention
In multi-variate models, tamoxifen duration, age, prior post-menopausal HT, and endoxifen levels all predicted side effects
I was hoping that my hips and low back ache constantly would cease, but I'm sure the Neulasta played a part
My choices: have hysterectomy and keep taking Tamoxifen or stop taking it, maybe start an AI
In women with breast cancer, the use of hormone replacement therapy or oral contraceptives to manage tamoxifen side effects is a relative contraindication
Hot flashes
Treatment — which could include surgery, hormone-blocking pills, targeted radiation or a combination of these therapies — depends on the characteristics of the tumor
In women, the adverse effects (AEs) of tamoxifen have been well-studied (Brown, 2002; Fisher et al
Compared to other forms of cancer treatments, it has relatively few serious side effects
There are many things you can do to help prevent and manage side effects
In young women who have had treatment to stop the ovaries producing oestrogen (ovarian suppression) followed by aromatase inhibitor therapy, bone density can be lost more quickly
Both tamoxifen and raloxifene can lower the risk of invasive breast cancer (tamoxifen by about 50% and raloxifene by about 38%) in women at high risk* [1]
Hence, our results are particularly relevent to premenopausal women with ER-positive disease—and, young women protected by 10 years of tamoxifen from death from breast cancer gain Researchers analyzed the medical records of 64 male breast cancer patients treated at MD Anderson between 1999 and 2009
Mood changes 6
Tamoxifen is used to treat breast cancer in both premenopausal women (women who have not yet
What is the most common side effect of taking tamoxifen? Tamoxifen side effects may include: Menopause-like symptoms, including hot flashes, night sweats and vaginal
Breast Cancer Risk and Prevention Download Section as PDF Tamoxifen and Raloxifene for Lowering Breast Cancer Risk On this page [ show] Tamoxifen and raloxifene have
Out of 48 predefined symptoms, five were associated with tamoxifen exposure (hot flashes, night sweats, cold sweats, vaginal discharge and muscle cramps)
SAN ANTONIO — Low-dose tamoxifen, sometimes called “baby TAM,” is gaining traction as an alternative to full-dose tamoxifen
Study looks at why young women don’t start treatment or cut it short
It is used to reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma Tamoxifen is indicated for the treatment of breast cancer in a variety of settings
Side effects include dry mouth, dizziness, drowsiness, and sleep problems
This approach would also pose substantial challenges to young patients regarding childbearing and anti-estrogenic side effects
Less common but serious side effects of hormone therapy drugs are listed below
However, only a small number of young women have been exposed to tamoxifen in utero, and a smaller number have
In women, tamoxifen is an option for those who have been through menopause and those who haven't
The first endocrine therapy was surgical oophorectomy in young women with randomised postmenopausal women to tamoxifen or anastrozole for 5 years
The researchers looked at the results from women treated with tamoxifen alone, with tamoxifen plus ovarian suppression, and with exemestane plus Another aspect of patient perceptions about tamoxifen identified in our study was the concern about side effects
Both drugs carry an increased risk of blood clots, though the risk may be lower with raloxifene
During the first period, treatment interruptions were associated with a lack of understandable information about endocrine Nevertheless, because these drugs are so widely used, the related eye conditions may affect many women
5 and 5 mg) versus high-dose (10 and 20 mg) tamoxifen, the difference of severity from start to end of treatment was 34% lower Currently, there is not enough evidence to recommend routine testing for the CYP2D6 genotype when making clinical decisions regarding the use of tamoxifen in either pre or post menopausal women
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Hi @sparklegram I encourage you to do research on hormone-blocking long-term side effects
Tamoxifen is the hormonal therapy drug used most often to lower the risk that DCIS or LCIS will lead to an invasive breast cancer
Tamoxifen: the effects of this medication are variable; some pre-menopausal women note dryness due to the effect of tamoxifen blocking oestrogen in the lining of the vagina while others experience more vaginal discharge