In combination with aspirin, clopidogrel is often used as part of dual antiplatelet therapy (DAPT) for the secondary prevention of ACS
Block phosphodiesterase, resulting in decreased reputable of adenosine and elevated levels of cAMP and gAMP
To improve the efficacy over antiplatelet monotherapy, dual antiplatelet therapy (DAPT) has been increasingly adopted in the management of non
Double‐blinded, placebo‐controlled randomized trial
Antiplatelet effects of aspirin treatment are inconsistent at dosages ≤2 mg/kg q24h,6 and administration of aspirin at 2 mg/kg q24h with prednisone is associated with
The active metabolite has an elimination half-life of about 8 hours
Combination antiplatelet therapy with clopidogrel and aspirin may reduce the rate of recurrent stroke during the first 3 months after a minor ischemic stroke or transient ischemic attack (TIA)
Routine medications were prescribed to resume for a patient who returned from major knee surgery 1 hour ago
If the procedure requires discontinuation of antiplatelet therapy, the last intake of ASA, clopidogrel, ticagrelor, and prasugrel 3, 5, 5, and 7 days before surgery, respectively, is proposed (Table 3)
The 2018 Guidelines for Management of Acute Ischemic Stroke state that clopidogrel and aspirin could be
Introduction
APT refers to antiplatelet therapy
In this review, we evaluated the recent guidelines in non-cardiac, cardiac, and regional anesthesia
Dual-antiplatelet therapy (DAPT) prevents thrombotic complications associated with coronary artery disease, acute coronary syndrome, and stent thrombosis following the percutaneous coronary intervention or coronary artery bypass grafting
Cardiovascular literature has found aspirin‐based dual antiplatelet therapy using half‐dose ticagrelor (45 mg BID [T45]) to be superior to standard‐dose clopidogrel (75 mg once daily) in achieving lower P2Y12 reaction units without resulting in an increased incidence of intracranial hemorrhage
com trial (Cilostazol Stroke Prevention Study combination) showed that DAPT using cilostazol was more
Antiplatelet therapy is used for both the management of acute ischemic stroke and for the prevention of stroke
2018; 391:850–859