, 150000/microliter (for adults) is defined as thrombocytopenia
Sodium valproate and thrombocytopenia – a common adverse reaction
When medicines or drugs cause a low platelet count, it is called drug-induced thrombocytopenia
Of these, 17
Abstract Objective: To investigate the relationship between platelet count and serum valproic acid level, age, duration of valproic acid therapy, and polytherapy, and to
In adults, platelet
PMID: 10513686 DOI: 10
Liver disease or Valproic acid may cause serious allergic reactions affecting multiple body organs (eg, liver or kidney)
Either decreases toxicity of the other by pharmacodynamic synergism
normal menstrual bleeding occurring earlier, possibly lasting longer than expected
The platelet count should be monitored for patients receiving a high concentration of valproic a
Age older than 65 years (p=0
VPA caused decreased factor VII levels, platelet count, factor VIII, protein C, fibrinogen and increased lipoprotein (a) levels even during short-term therapy, in newly diagnosed Thrombocytopenia (low platelet count) or Viral infection (eg, HIV, cytomegalovirus infection)—Use with caution
Depression: Some people get suicidal when taking valproic acid , so it is used cautiously in people with depression or a history of depression
Introduction Valproic acid (VPA) is a frequently prescribed anti-epileptic drug
Valproic acid (VPA), a widely used antiepileptic drug, is one of the common causes of drug-induced thrombocytopenia
2) Our data suggest a significant relationship between impaired platelet function and both VPA dose and plasma concentration
Valproic Acid / adverse effects* Vitamin B 12 / blood Substances Valproic Acid On Day 26, we discontinued quetiapine and shifted the medication to 4 mg/day of risperidone, while maintaining the valproic acid treatment
1982 Sep;57 (9):681-4
Haematological effects Anti-epileptic drugs (AEDs), especially valproic acid (VPA), are the main treatment of choice
2 ) Although his valproic acid level did not change on the day he presented to the clinic, his white blood cell count was 3300/mm 3 with 32% Pelger–Huët cells and a platelet count of 42,000/mm 3
8 years) before and after valproate 500 mg and compared the results to levetiracetam 1000 mg as a control substance and placebo
Describes how platelet count test is used, when platelet count test is requested, Drugs/medication – some medications (such as penicillin, gold used to treat arthritis, furosemide, valproic acid and others) can affect platelet production
However, to date, few studies describe the occurrence of macrocytosis as an adverse effect of divalproex