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Acetaminophen and paracetamol are categorized as both non-opioid analgesics (pain relievers) and antipyretic agents (fever relievers)
IUPAC Standard InChI: InChI=1S/C8H9NO2/c1-6 (10)9-7-2-4-8 (11)5-3-7/h2-5,11H,1H3, (H,9,10) Copy Sheet of paper on top of another sheet
Alterations of peripheral nociceptive transduction and transmission are the main targets of effect, with paracetamol possibly modulating central pain pathways as well
Structure
Melting point 169-171℃, relative density 1
It is used widely by parents and health professionals and it has analgesic and antipyretic effects
Function and mechanism of action
Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs (e
Side effects depend on the specific drug, its dose and duration of use, but largely include an increased risk of Chemical structures of: a paracetamol, b pseudoephedrine HCl and c brompheniramine maleate
Brief history of paracetamol
Whether you call it acetaminophen (in the United States and Japan) or paracetamol (in Europe and most of the rest of the world), it’s one of the most widely used pain relievers
rugosa was studied in paracetamol (750 mg/mg)- and CCl 4 (1
The mechanism of action is complex and includes the effects of both the peripheral (COX inhibition), and central (COX, serotonergic descending neuronal pathway, L-arginine/NO pathway, cannabinoid system) antinociception processes and "redox" mechanism