Tamoxifen for breast cancer

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  • Other forms work by decreasing the body's production of hormones
  • Jun 5, 2006 · Tamoxifen is a drug, taken by mouth as a pill
  • Hormone therapy is sometimes used to treat breast cancer
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  • Warnings
  • 6 min read
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  • Tamoxifen may cause wanted and unwanted effects
  • Introduction
  • Hormone therapy slows or stops the growth of hormone-sensitive tumors by blocking the body’s ability to produce hormones or by interfering with effects of hormones

    This prevents cancer cells from growing

    Tamoxifen is used to reduce the risk of invasive breast cancer if you're at high risk and you're 35 and older, whether or not you've gone through menopause

    Grading

    Tamoxifen is also used to lower a woman's chance of developing breast cancer if she has a high risk (such as a family history of breast cancer)

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    Introduction

    Introduction

    Tamoxifen works by blocking the receptors and this prevents oestrogen from reaching cancer cells

    Recommendation

    Tamoxifen (TAM) is known to have a dual mechanism of action: (1) to compete with 17β-estradiol (E 2) at the receptor site and to block the promotional role of E 2 in breast cancer; and (2) to bind DNA after metabolic activation and to initiate carcinogenesis

    Adult 20 mg daily

    It’s used alone and with other drugs as part of endocrine therapy

    Ductal carcinoma in situ (DCIS)

    A 2005 meta-analysis (see the journal abstract) indicated that 5 years of tamoxifen treatment is better than 1 to 2 years of treatment at preventing breast cancer recurrence and death in women with early breast

    ENDING SOON: 21% Off w/Code: USA21 Menu In combination with chemotherapy, using supplements is worrisome because of potential drug-herb interactions

    Tamoxifen, known by the brand names Nolvadex and Soltamox, is a chemo drug given to women with Estrogen Receptor-Positive (ER Positive) Breast Cancer, including Early Stage ER-Positive Breast Cancer

    Tamoxifen in the treatment of breast cancer

    Author C K Osborne 1 Tamoxifen / adverse effects Novartis, the maker of letrozole, provided funding for the trial, along with NCI and the International Breast Cancer Study Group

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