Fourteen patients with neuroleptic-induced akathisia were treated with propranolol in an open trial
The improvement in akathisia from propranolol could thus be due to the β 2 blocking property of propranolol
Propranolol in the treatment of neuroleptic-induced akathisia Published Online: 1 Apr 2006 View article Share Abstract
beta-Blockers, particularly propranolol, have been shown to be an effective treatment for neuroleptic-induced akathisia (NIA)
In small clinical trials, propranolol and benztropine have shown evidence of efficacy in the treatment of akathisia
Compare risks and benefits of common medications used for Akathisia
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We treated nine patients who had neuroleptic-induced akathisia with low doses (25-100 mg/day) of the beta-blocker metoprolol
I get mine off my GP,if you don't ask you don't
1987 Aug;7(4):279-80
Akathisia is a clinical syndrome characterized by the subjective sense of unease or restlessness, or observable motor manifestations including shuffling or tramping movements of the legs and feet [Barnes and Braude, 1985]
Doses required for improvement were low (30-80
The goal of this guideline is to provide clinicians with recommendations on the assessment and treatment of akathisia
Raters and patients were "blind" to treatment
Antipsychotic-induced akathisia is optimally managed by reducing the medication dose
May be taken with or without food
Beta-blockers such as propranolol and benzodiazepines have historically been used for the treatment of akathisia although the amount of high-quality data supporting their use is limited
For people with neuroleptic‐induced acute akathisia
If ineffective, a trial with propranolol may be useful as well as the addition of a 5-HT 2A antagonist like mirtazapine or mianserine
Subtypes of akathisia have been described which include acute, chronic, tardive, and withdrawal akathisia
Compared the effects of propranolol (80 mg/day), benztropine (6 mg/day), or placebo on akathisia for 28 patients (aged 27–73 yrs)
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This video by Dr Sanil Rege covers the pathophysiology, diagnosis and management of akathisia
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