Cyproheptadine dosing, indications, interactions, adverse effects, and more Advanced age is associated with reduced clearance and greater risk of confusion, dry mouth, constipation, and other A systematic review identifying the use of cyproheptadine (CY) as an appetite stimulant was completed
Appetite Stimulant
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Cyproheptadine has also been used off-label as an appetite stimulant and to treat cyclic vomiting
Includes Cyproheptadine indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more
Cyproheptadine is a drug that has many uses but is often prescribed to cats because of the side effect of appetite stimulation that it causes
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand
Cyproheptadine, an antihistamine and antiserotonergic agent, is an appetite stimulant that is efficacious in promoting weight gain in children and adults with poor appetite
appetite changes, weight gain, restlessness or excitability (especially in children), numbness or tingly feeling, increased sweating or urination, thickening of mucus in the nose/throat, or
In addition, CPH can stimulate the appetite by Most had lost weight on stimulant alone (mean weight loss was 2
87, p < 0
2005 Sep;40(3):251-6
A systematic review of cyproheptadine, an antihistamine, as an appetite stimulant in all age groups found that 39 of the 46 studies reported that cyproheptadine resulted in significant weight gain (Appetite 2019;137:62–72)
Background: Cyproheptadine, an appetite stimulant, has been used in poor-appetite underweight children
Despite numerous studies showing that cyproheptadine achieved positive outcomes, studies documenting its effectiveness on appetite are limited
Cyproheptadine overdosage, particularly in infants and young children, may produce hallucinations, CNS depression, seizures
Most agents have side effects that limit their usefulness solely as an appetite
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