Valproic acid is also used to treat the manic phase of bipolar disorder (manic-depressive illness), and helps prevent migraine headaches
Valproic acid is a carboxylic acid designated as 2-propylpentanoic acid
Valproic acid (VPA) ia as a highly prevalent medication with multifaceted therapeutic applications in various neurological and psychiatric disorders
The tablet form of the medication comes in 2 variations, which include a
Valproic acid: Alternatives: Lamotrigine: Clonazepam: Zonisamide: Levetiracetam: 2
Azopt
Find medical information for valproic acid on epocrates online, including its dosing, contraindications, drug interactions, and pill pictures
Management: Avoid concomitant use of Synacthen Depot (dosage form available in Canada) with valproic acid
Explanation: FDA has concluded that valproic acid is a narrow therapeutic index (NTI) drug based on the following evidence: The range between the effective valproic acid concentrations and the concentrations associated with serious toxicity is narrow; Sub-optimal doses or concentrations lead to therapeutic failure or
See also Warning section
Diarrhea, dizziness, drowsiness, hair loss, blurred/ double vision, change in menstrual periods, ringing in the ears, shakiness (tremor), unsteadiness Therapeutic drug monitoring (TDM) is recommended during valproic acid (VPA) use, and total serum concentration has been widely adopted
Valproic acid (VPA) is a branched short-chain fatty acid derived from naturally occurring valeric acid
Generic Name Valproic acid DrugBank Accession Number DB00313 Background
blurred vision
It may also cause some people to have suicidal thoughts and tendencies or to become more depressed
Containing 269
Since valproic acid may interact with concurrently administered drugs that are capable of hepatic enzyme induction, periodic determinations of plasma concentrations of valproic Divalproex (Depakote) and valproic acid are both antiepileptics used to treat certain types of seizures
Note: Multiple pictures are displayed for those medicines available in different strengths, marketed under different brand names and for medicines manufactured by different pharmaceutical companies
Navigate to section
However, the free form of VPA is responsible for its pharmacologic and toxic effects, and the total and free concentrations are highly discordant because of VPA’s highly protein bound and
Therefore, the total daily dose is divided into 4 doses for the liquid formulation and 2 doses for modified-release tablets
Brand names: Valproate Sodium, Depakene, Depacon, Stavzor Drug class: fatty acid derivative