A single report described use of subcutaneous ondansetron via a microinfusion pump in 521 pregnant
Ondansetron is frequently used to treat nausea and vomiting during pregnancy, but the safety of this drug for the fetus has not been well studied
First trimester ondansetron use is associated with an increased risk of neonatal VSD potentially driven by higher doses
Most research
Of 3,317 pregnant women in the study, 263 (8 percent) developed pregnancy-related high blood pressure, 402 (12 percent) got gestational diabetes, and 82 (2
It is important to emphasise that ‘first trimester’ means exposure up
Before your doctor prescribes any medications or supplements for morning sickness, you may want to try a few lifestyle adjustments
Dec 18; 320 Nausea and vomiting are most common and most severe during the 1st trimester
Nausea and vomiting and hyperemesis gravidarum typically occur during the first trimester, the sensitive time for exposure to teratogens because First trimester exposure to ondansetron was associated with increased risk of cardiac (OR: 1
76-2
The European Medicines Agency (EMA) responded to say that their statement is not referring to women with severe nausea and vomiting in pregnancy
’ 73 They summarised the data for congenital My OB was perfectly fine with me taking zofran during my first trimester, and baby is doing fine (27 weeks today)
US FDA pregnancy category: B
Over the last decade drugs that reduce chemotherapy-induced emesis (the 5-hydroxytryptamine 3 inhibitor, ondansetron, and metoclopramide) have
Zofran and pregnancy
1 About one-third of women with nausea and vomiting in pregnancy have symptoms that are clinically significant
The risk is something like 1
A new study published in the New England Journal of Medicine concluded that the popular drug Zofran (used to treat nausea, vomiting and in some cases, hyperemesis gravidarum, in early pregnancy) poses no risk to the developing fetus
Warnings Against Zofran During Pregnancy
A detailed analysis of drug utilization in our study will be provided in a future publication
A study published in 2012 examined over 10,000 pregnant women who suffered from morning sickness, discovering a twofold risk of birth defects in women taking ondansetron during the first trimester of pregnancy
The discomfort will likely decrease after a few weeks as your body adjusts to hormonal changes