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    Sevelamer treatment also results in a lowering of low-density lipoprotein (LDL) and total serum cholesterol levels

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    It binds phosphate from food in the digestive tract and so reduces serum phosphorus levels in the blood

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    When taken with meals, it binds to dietary phosphate and prevents its absorption

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    Dose should be initiated based on serum phosphorus level: >5

    After 8 weeks of sevelamer treatment, uremic mice exhibited a significantly lower degree of atherosclerosis (P<0

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