intramuscular, or rectal prochlorperazine (Compazine) are recommended for treatment of patients with nausea and acute migraine
There may be a slightly increased risk of serious, possibly fatal side effects (such as heart failure, fast/irregular heartbeat, pneumonia) when this medication is used by older adults
Prochlorperazine may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use
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Antihistamines such as meclizine (Antivert) are associated with minor side effects involving the central nervous system, such as confusion, sedation, dizziness
Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage
Prochlorperazine side effects
Analyses of 17 placebo-controlled trials (modal duration of 10 weeks), largely in
Prochlorperazine may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use
If any of these effects last or get worse, tell your doctor or pharmacist promptly
Prochlorperazine may cause anticholinergic side effects such as dry mouth, constipation, dry eyes, decreased urinary output, and mental confusion
Cons
• Available as an oral tablet or suppository for treating nausea and vomiting
Zofran and Compazine belong to different drug classes
DrugBank
5-10mg PO or IV q6-8 hours; Max: 40mg/day; Pediatric Dosing Lactation risk: Safety unknown; Renal Dosing: not defined; Hepatic Dosing: not defined; Contraindications
2
Compazine Injection may be administered either undiluted or diluted in isotonic solution
Drowsiness, dizziness, lightheadedness, blurred vision, constipation, or dry mouth may occur
Compazine Uses, Dosage, Side Effects, Food Interaction and all others data
swelling of the eyes, face, mouth, lips, tongue, throat, arms, hands, feet, ankles, or lower legs
Tell all of your health care providers and lab workers that you take this medicine (prochlorperazine tablets)
Eat a small amount of bland food, like saltines
Tell your doctor if your condition persists or worsens
Classification
unusual bleeding or bruising