It is used to treat stomach-related issues, such as nausea and vomiting, as well as stomach pain and discomfort caused by decreased movement of the stomach and upper
Some patients may require higher doses up to 20 mg three or four times daily
Significant adverse effects are cardiac arrhythmias and hyperprolactinemia
Background Domperidone is a useful alternative to metoclopramide for treatment of gastroparesis due to better tolerability
57; P-score =
Medication noted in the study included MCP, domperidone, tegaserod, erythromycin, proton pump inhibitors (PPIs), and cyproheptadine
Domperidone has been associated with cardiac dysrhythmias; it should be
If needed, the dose could be increased to 20 mg 3 or 4 times a day, with the maximal dose of 80 mg/day
Treatment of nausea/vomiting Identification Summary
Domperidone Adult Medication Guideline Page 2 of 4 Gastroparesis Oral: 10mg three times a day, for up to 4 weeks
Aim To describe the outcome of treating patients with refractory gastroparesis symptoms with domperidone
Domperidone is a peripheral D 2 receptor antagonist and is used as a prokinetic and antiemetic of low therapeutic efficacy
A gastroparesis diet includes liquid and solid foods that are easy for the stomach to mix and empty
Erythromycin, a macrolide antibiotic, improves gastric emptying through stimulating the
The duration of domperidone therapy ranged from 3 months to 4 years with a mean of 8 months
The following outcome measures were identified: change from baseline in Gastroparesis Cardinal Symptom Index total score, with 3 subscales, plus Gastroesophageal Reflux Disease and Patient Assessment of Upper Gastrointestinal Disorders-Quality of Life scores
It’s not normally available in the U
12 Medications for Gastroparesis: Domperidone (motilium) It is a drug that is used most often to treat nausea and vomiting associated with chemo or radiation in cancer patients
Domperidone should be avoided in patients with prolonged QTc (>470 ms in males, >450 ms in females)
Cats show dose-dependent excitation, aggressiveness, and motor impairment
Parkman,§ Thomas Abell,jj Kenneth L
These AEs were also observed among patients receiving domperidone to treat gastroparesis