Harvoni use in pregnancy

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  • Harvoni is a medication used to treat chronic hepatitis C infection
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  • are pregnant or plan to become pregnant
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  • Harvoni comes as a tablet (pill) that you swallow
  • Ledipasvir/sofosbuvir, in
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  • This drug can interact with other medications and some supplements
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  • The usual duration of treatment is between 8 and 12 weeks
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  • 3 Females and Males of Reproductive Potential 8

    Both men and women using ribavirin should use effective birth control to prevent pregnancy

    The FDA approved ledipasvir combined with sofosbuvir in one tablet (Harvoni®) for the treatment of hepatitis C genotypes 1, 4, 5, and 6

    other drugs How to take How it works Pregnancy Breastfeeding Side Effects Drug Interactions In short, Harvoni could be used during pregnancy, but only if the potential benefit justified the potential risk to the fetus

    Background Nutritional status during pregnancy can have a significant impact on infant and maternal health outcomes

    Takeaway

    This is big change from ribavirin’s dire Black Box warnings of potential

    Two late pregnant women and one female infant with severe CHC were enrolled for treatment

    No adequate human data are available to establish whether or

    For a general overview of the drug, including details about its uses, see this article

    This treatment is used only when needed during pregnancy

    Refer to the ribavirin prescribing information for more information on ribavirin-associated risks of use during pregnancy

    Ribavirin may cause birth defects if either partner is using it during conception or pregnancy

    If HARVONI is administered with ribavirin, the combination regimen is contraindicated in pregnant women and in men whose female partners are pregnant

    WARNING: Although this medication is used to treat hepatitis C, it may rarely make another liver problem called hepatitis B get worse

    HARVONI is a prescription medicine used to treat adults with chronic (lasting a long time) hepatitis C (Hep C) genotype (GT) 1, 4, 5 or 6 infection with Use of HARVONI with P-gp inducers is not recommended

    Dosage form: Tablets and Oral Pellets

    o Males and females who take HARVONI in combination with ribavirin should also read the ribavirin Medication Guide for important pregnancy, contraception, and infertility information

    Harvoni was given to treat chronic (long-term) infection with hepatitis C virus in adults and children from 3 years of age

    A generic drug contains an exact copy of the active drug in a brand-name medication

    In those with GT 1 and advanced cirrhosis (decompensated) or with GT 1 or 4 with or without cirrhosis (compensated) who have had a liver transplant, HARVONI It is a combination of two medications, sofosbuvir and ledipasvir

    In those with GT 1 and advanced cirrhosis (decompensated) or with GT 1 or 4 with or without cirrhosis (compensated) who have had a liver transplant, HARVONI

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