Fenofibrate is a third-generation fibric acid derivative indicated as a monotherapy to reduce elevated low-density lipoprotein cholesterol, total cholesterol
Abstract This discussion outlines the major aspects of the human pharmacology of fenofibrate, a hypolipidemic agent
On This Page Indications and Usage Dosage and Administration Dosage Forms and Strengths
Each capsule contains 67 mg, 134 mg or 200 mg of
This discussion outlines the major aspects of the human
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These symptoms may include fever, rash, loss of appetite, nausea, vomiting, fatigue, stomach pain, dark urine, yellow skin or eyes, or abnormal liver enzymes
Its lipid lowering activity is probably mediated by its interactions with the peroxisome proliferator activated receptor alpha (PPARα), which regulates gene expression of enzymes involved in fatty acid oxidation
Mechanism of action Clofibrate was available previously in generic forms and under the brand name of Atromid-S as capsules of 500 mg
Learn and reinforce your understanding of Antihyperlipidemics - Fibrates: Nursing pharmacology
It is indicated to reduce total cholesterol, low-density lipoprotein (LDL), apolipoprotein B (apo B), and non-high-density lipoprotein (HDL) in patients with primary
Oral terbinafine is >70% absorbed but only 40% bioavailable after first pass metabolism, reaching a C max of 1µg/mL with a T max of 2 hours an an AUC of 4
Antihyperlipidemic Drugs lower serum levels of cholesterol and various lipids
9 It is also indicated to reduce the risk of myocardial infarction (MI), stroke, coronary revascularization, and cardiovascular death in adult patients with
There are three agents of choice in the fibric acid drug class: fenofibric acid, fenofibrate, and gemfibrozil
Functions also as histamine receptor and mediates cellular responses to histamine P14867
, Clofibrate
Fenofibrate is part of a class of drugs known as antihyperlipidemics, specifically a fibrate
If pharmacologic therapy is needed, statins are first-line drugs TRICOR (fenofibrate tablets), is a lipid regulating agent available as tablets for oral administration
Atorvastatin competitively inhibits 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase
1989;76(suppl 1):33-44
It is used to mimic the basal levels of insulin in diabetic individuals