Fenofibrate pharmacological classification

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  • 6 times the human dose), and gemfibrozil (250 mg/kg; 1
  • Pharmacology of fenofibrate
  • A
  • Consider therapy modification
  • This is not a complete list of side effects and others may occur
  • B = Class warning
  • Fenofibrate is a third-generation fibric acid derivative indicated as a monotherapy to reduce elevated low-density lipoprotein cholesterol, total cholesterol

    Abstract This discussion outlines the major aspects of the human pharmacology of fenofibrate, a hypolipidemic agent

    On This Page Indications and Usage Dosage and Administration Dosage Forms and Strengths

    Each capsule contains 67 mg, 134 mg or 200 mg of

    This discussion outlines the major aspects of the human

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    These symptoms may include fever, rash, loss of appetite, nausea, vomiting, fatigue, stomach pain, dark urine, yellow skin or eyes, or abnormal liver enzymes

    Its lipid lowering activity is probably mediated by its interactions with the peroxisome proliferator activated receptor alpha (PPARα), which regulates gene expression of enzymes involved in fatty acid oxidation

    Mechanism of action Clofibrate was available previously in generic forms and under the brand name of Atromid-S as capsules of 500 mg

    Learn and reinforce your understanding of Antihyperlipidemics - Fibrates: Nursing pharmacology

    It is indicated to reduce total cholesterol, low-density lipoprotein (LDL), apolipoprotein B (apo B), and non-high-density lipoprotein (HDL) in patients with primary

    Oral terbinafine is >70% absorbed but only 40% bioavailable after first pass metabolism, reaching a C max of 1µg/mL with a T max of 2 hours an an AUC of 4

    Antihyperlipidemic Drugs lower serum levels of cholesterol and various lipids

    9 It is also indicated to reduce the risk of myocardial infarction (MI), stroke, coronary revascularization, and cardiovascular death in adult patients with

    There are three agents of choice in the fibric acid drug class: fenofibric acid, fenofibrate, and gemfibrozil

    Functions also as histamine receptor and mediates cellular responses to histamine P14867

    , Clofibrate

    Fenofibrate is part of a class of drugs known as antihyperlipidemics, specifically a fibrate

    If pharmacologic therapy is needed, statins are first-line drugs TRICOR (fenofibrate tablets), is a lipid regulating agent available as tablets for oral administration

    Atorvastatin competitively inhibits 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase

    1989;76(suppl 1):33-44

    It is used to mimic the basal levels of insulin in diabetic individuals

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