This project was aimed to formulate and characterize mucoadhesive buccal tablets of aceclofenac, utilizing different proportions of three polymers carbopol 934, hydroxypropyl methylcellulose, and sodium carboxymethylcellulose
Jan 1, 2015 · N Jain
Cold sores are a sore subject for many, which is why Sitavig (acyclovir), 50mg Muco-Adhesive Buccal Tablet is such a breakthrough in the world of prescription cold sore treatment
SITAVIGTM (acyclovir mucoadhesive buccal tablets) is indicated for the treatment of recurrent herpes labialis (cold sores) in immunocompetent adults
Ankita Saxena; is easily accessible for self-medication and can be
Muco-Adhesive Buccal Tablet applied to the upper gum over the canine fossa Targeted delivery of antiviral drug directly to the site of viral replication Stays active during viral
Hence, the results concluded that buccal mucoadhesive aceclofenac tablets can be formulated
Carrageenan-based acyclovir mucoadhesive vaginal tablets for prevention of genital herpes: 27: Paczkowska et al (2020) Inter-batch comparison (n* = 6) and
been developed as a local extended-release mucoadhesive buccal tablet in order to optimize local delivery of acyclovir
The drug is a muco-adhesive tablet, applied to the upper gum at the onset of prodromal symptoms
This new product can deliver high concentration of acyclovir ²SK Tyring, el al
, a single application of acyclovir mucoadhesive buccal tablet reduces recurrence of herpes labialis in a randomized double-blind phase 3 study: Exploratory results, Journal of Buccal mucoadhesive dosage forms can also be categorized into three types on the basis of geometry
Tablets were prepared by using hydroxyethyl cellulose (HEC) and carbopol 940 in a 1:1 ratio as matrix-forming Acyclovir Lauriad ®: A muco-adhesive buccal tablet for the treatment of recurrent herpes labialis « In clinical trials, a single application of acyclovir muco-adhesive buccal tablet resulted in high exposure of acyclovir to saliva and oral mucosa, and levels were sustained for 24 h
In this context, buccal films capable of providing higher residence time in the oral cavity together with their potential to release the molecules for a prolonged period of time are proposed [20], [21]
The
The delayed-release buccal tablet is usually applied with a dry-finger within 1 hour after cold sore symptoms (itching, redness, burning or tingling) begin, but before the cold sore appears
This is a major advantage over oral acyclovir as it requires frequent dosing due
Treatment for: Cold Sores