Highlights
villosum and to elucidate the molecular mechanisms
Glucocorticoids have a pivotal role in the glucose, protein, and fat
Anti-inflammatory effects are
Therapeutic glucocorticoids are powerful, broad-spectrum anti-inflammatory agents that are limited by a wide range of adverse effects
5 Dexamethasone (DEX) is a potent synthetic glucocorticoid used for the treatment of variety of inflammatory and immune-mediated disorders
Dexamethasone is a synthetic glucocorticoid used for its anti-inflammatory and analgesic effect
Dexamethasone and flumethasone (short-acting formulations) can induce parturition when administered after 255 days of gestation in cattle, but induced calving is usually associated with a high incidence of adverse effects, including retained placenta
Dexamethasone is also used to treat ulcerative colitis, arthritis, lupus, psoriasis, and breathing disorders
and this may well explain Abstract
Examples include Advil and Motrin (ibuprofen), Aleve (naproxen) and aspirin
; (4) maintaining the normal physiological functions of organs and
However, glucocorticoids are generally harmful for infectious diseases, such as bacterial sepsis and severe influenza pneumonia, which can develop respiratory failure and systemic inflammation similar to COVID-19
It also increases the gene expression of IL-10, which is an anti-inflammatory cytokine mediator (Azimi, S