The Combination of Leflunomide (Arava) and Methotrexate is Safe & Efficacious for the Treatment of Rheumatoid Arthritis
Combining these medications may increase
Leflunomide is a medication that treats rheumatoid arthritis
Both leflunomide and methotrexate are efficacious for prolonged treatment of RA
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Arava belongs to a group of drugs called disease-modifying antirheumatic drugs
In a double-blind, randomized, controlled trial in early RA, initial treatment with methotrexate–doxycycline combination therapy was superior to methotrexate alone
Leflunomide is used to relieve symptoms caused by active rheumatoid arthritis, such as inflammation, swelling, stiffness, and joint pain
Methotrexate is a drug used for conditions such as cancer, rheumatoid arthritis, psoriasis, and ectopic pregnancies
Drugs That May Cause Photosensitivity
In rheumatoid and psoriatic arthritis this action helps to reduce inflammation and thus reduces pain and swelling in the joints
This medicine is available only with your doctor's prescription
Effectiveness
Arava (leflunomide) is a brand-name prescription medication
The patient had been taking leflunomide 20 mg alternate days and prednisone 10 mg per day
Methotrexate is recommended over leflunomide because of lower cost and better dosing flexibility
However, there are also well documented reports of the efficacy of this combination
Learn about the common, mild, and serious side effects it can cause and how to manage them