It is in this spirit that, over the objections of his peers, and no doubt because of them, too, he has promoted a combination of hydroxychloroquine, an antimalarial
Rarely, acute Q fever manifests as encephalitis or meningoencephalitis
It's also used to treat symptoms of rheumatoid arthritis, discoid and systemic lupus erythematosus
2 Q Fever
Most commonly reported in southern France and Australia, Q fever occurs worldwide (except in New Zealand)
Effective treatment and vaccines are available for this condition
Doxycycline and hydroxychloroquine are the treatment combination most utilized by healthcare providers to treat Q fever endocarditis or osteomyelitis in children, but a variety of Chronic Q fever includes mainly endocarditis and other endovascular infections and, more rarely, osteoarticular infections
Mortality prior to 1999 was 28%, compared with 5% for more recent cases
BACKGROUND Q fever endocarditis, caused by Coxiella burnetii, is fatal in 25% to 60% of patients
The results of this report indicate that doxycycline and hydroxychloroquine may be the preferred treatment for chronic Q fever
, ciprofloxacin) or rifampin for at least 3–4 years
Initial dose: 400 to 600 mg salt (310 to 465 mg base)/day orally divided in 1 or 2 doses
Given the diagnosis of acute Q fever with vascular involvement, he was started on doxycycline 100 mg bid and hydroxychloroquine 200 mg tid
Psychosis likely induced by hydroxychloroquine in a patient with chronic Q fever: a case report and clinically relevant review of pharmacology Psychosomatics