Is Zofran safe during pregnancy? Doctors frequently prescribe ondansetron to treat nausea and vomiting during pregnancy
Ondansetron Pregnancy and Breastfeeding Warnings
Ondansetron is a medication used to treat nausea and vomiting following surgery, chemotherapy, or radiation therapy
Although Zofran is typically used to treat nausea and vomiting in cancer patients and those who struggle with migraines, doctors do sometimes prescribe Zofran
Getty Images Learn more about this medication prescribed for morning sickness and find out whether it's safe to take during pregnancy or not
The drug is not labeled for use in NVP in either the United States or Canada
Hyperemesis gravidarum describes nausea and vomiting that is severe enough to cause fluid and electrolyte disturbances, and often requires hospitalization
Albeit based on limited human pregnancy data, ondansetron has not been associated with a significantly increased risk of birth defects or other adverse pregnancy
Prescribe ondansetron with caution to people with: QT interval prolongation — for example electrolyte disturbances and use of drugs that prolong the QT interval
Ondansetron, a potent antiemetic agent, is a 5-hydroxytryptamine receptor 3 antagonist that blocks the effects of serotonin
9% of ondanestron-exposed
I didn't take it every day in the third trimester but probably 2-3x weekly
(1) nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy
You may report side effects to FDA at 1-800-FDA-1088
It is also used to prevent nausea and vomiting that may occur after surgery
Animal studies have not shown an increased risk of infertility, birth defects or other adverse reproductive outcomes and there are limited data available about human pregnancy outcomes following exposure to ondansetron
Generally described, these categories are: A: There is no risk to the fetus in the first trimester based upon adequate and well-controlled human studies
Data sources: PubMed, EMBASE, Cochrane, Scopus, Web of Science, Journals@Ovid Fulltext, ClinicalTrials
The FDA has approved a new medicine to treat nausea in pregnant women called Bonjesta, and doctors have prescribed less and less Zofran in 2020
6 percent in 2018
The safety of use of this medicine is a concern when used by pregnant women, especially in the first trimester, when the unborn child has fastest development of critical systems and general physical growth
Zofran lawsuits claim the manufacturer failed to warn patients of the possibility of birth defects associated with the anti-nausea drug