Retinal pigment changes and retinal toxicity can occur with prolonged use
The chemical name for hydroxychloroquine sulfate is 2-[[4-[(7-Chloro-4-quinolyl) amino]pentyl] ethylamino]ethanol sulfate (1:1)
8%), and rheumatologist recommendation
If any visual disturbance occurs (visual acuity, color vision), the drug should be immediately discontinued and the patient closely observed for possible progression of
discontinuation of Plaquenil may prevent life-threatening complications
•If cardiotoxicity is suspected, prompt discontinuation of PLAQUENIL may prevent life-threatening complications
Two months after the discontinuation of hydroxychloroquine
Hydroxychloroquine has endothelial stabilizing and anti-thrombotic effects
The molecular weight of hydroxychloroquine sulfate is 433
Hydroxychloroquine, initially used as an antimalarial, is used as an immunomodulatory and anti-inflammatory agent for the management of autoimmune and rheumatic diseases such as systemic lupus erythematosus
Cases of maculopathies and Stevens-Johnson syndrome, toxic epidermal necrolysis, photosensitivity and exfoliative dermatitis have been reported
Dis
This type of disease happens when the body's immune system attacks its own healthy tissue
Plaquenil is also used in certain children to treat and help Pharmacokinetics: Following a single 200 mg oral dose of PLAQUENIL to healthy male volunteers, the mean peak blood concentration of hydroxychloroquine was 129
3 ng/mL reached in 3
NEW ZEALAND DATA SHEET
However, due to the novel nature of the COVID-19, there is a lack of evidence about the specific risks of the disease in this patient group
1
Withdrawal of HCQ does not significantly increase the risk of flares in patients over 55 with quiescent SLE
PLAQUENIL is an antimalarial and antirheumatic indicated for the: • Treatment of uncomplicated malaria due to Plasmodium falciparum, Plasmodium malariae, Plasmodium ovale, and Plasmodium vivax in adult and pediatric patients
In its early form it appears reversible on discontinuation of Hydroxychloroquine
C1 and PICO 53