REVATIO (sildenafil) Injection: REVATIO is supplied as a clear, colorless, sterile, ready to use solution in a single-use vial containing 10 mg/12
Follow all directions on your prescription label and read all medication guides or instruction sheets
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Pharmacological Class Phosphodiesterase type 5 inhibitor (cGMP-specific)
persistent pulmonary HTN of newborn, refractory (off-label) [<1 mo] Dose: 0
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Sildenafil is used to treat erectile dysfunction (ED) and to reduce blood pressure in pulmonary arterial hypertension (PAH)
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Revatio (R): Oral: Initial dose: 5 or 20 mg orally three times a day, 4 to 6 hours apart Maximum dose: 20 mg orally three times a day Injection: Initial dose: 2
REVATIO is a prescription medicine that contains sildenafil, a drug used to treat pulmonary arterial hypertension (PAH) and improve exercise ability
These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly
Common side effects may include: nosebleed; headache; upset stomach; flushing (warmth, redness, or tingly feeling); sleep problems (insomnia); or • For most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity
88 to 2
The recommended adult dose of sildenafil for pulmonary hypertension is 20 mg 3 times daily
SUPER-2 (NCT00159887) Long-term Treatment of PAH
It’s meant to be taken as needed — about an hour before sex — but shouldn’t be You should consult your health care professional before taking any drug, changing your diet, or commencing or discontinuing any course of treatment
(Revatio® or Viagra®) or vardenafil (Levitra®)
Your doctor might increase the dose to 5 mg based on how you react to the medication
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It works by relaxing your blood vessels and lowering the blood pressure in your lungs, which makes it easier for your heart to pump blood to the rest of your body
5 milligrams (mg) once a day, taken at the same time each day, without regard for the timing of sexual activity
Taken with or without food
Dosage/Direction for Use