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USP are available containing atorvastatin calcium, USP equivalent to 20 mg of atorvastatin
Atorvastatin was not teratogenic in rats at doses up to 300 mg/kg/day or in rabbits at doses up to 100 mg/kg/day
New Atorvastatin calcium is a BCS class II drug, Similarity factor f2 was found to be 69
Atorvastatin crosses the rat placenta and reaches a level in fetal liver equivalent to that of maternal plasma
Dose selection for an elderly patient should be cautious, recognizing the greater frequency of decreased hepatic, renal Advanced age (≥65 years) is a risk factor for atorvastatin calcium-associated myopathy and rhabdomyolysis
Atorvastatin is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase
The 10 mg tablets are white to off-white, film-coated Uses
Atorvastatin was administered to pregnant rats and rabbits during organogenesis at oral doses up to 300 mg/kg/day and 100 mg/kg/day, respectively
14 mg atorvastatin calcium trihydrate) Excipients(s) with known effect: Atorvastatin is a selective, competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme responsible for the conversion of 3-hydroxy-3-methyl-glutaryl-coenzyme A to mevalonate, a precursor of sterols, including The recommended starting dose of atorvastatin calcium tablets are 10 or 20 mg once daily