Literature review current through: Dec 2023
Chloroquine inhibits pro inflammatory cytokine secretion induced by heme on macrophages
Abstract Chloroquine diphosphate (CDP) is a helpful tool in the blood bank for two main applications
Introduction
Delayed hemolytic transfusion reactions (DHTRs) in patients with sickle cell disease are underappreciated and potentially fatal
Since sensitized K 0 patients are rare, little is known about anti-Ku clinical relevance and in particular about its association to hemolytic disease of the fetus and newborn
A milder reaction is caused by anti-k, anti-Kp a, anti-Kp b, anti-Js a, and anti-Js b
Kidney disease or Liver disease—Use with caution
Chloroquine treatment for identification of Human Leucocyte Antigen (HLA) antibodies could not be done, which is the drawback of the study
The extent of hemolysis, and therefore the
The annual incidence of AIHA range from 1 to 3 in 100,000 to 1 in 25,000 individuals
Generally, most immunohematologists consider re-activity of HLA Other complications include
Post-transfusion purpura
The rationale supporting this practice is that replacement of blood loss should be beneficial for the patient
Hemolytic Transfusion Reactions
On reviewing the medical history of the patient, the nurse finds that the patient is also receiving digoxin
Iberis amara 3
Delayed hemolytic reaction
This is the most symptomatic complication of blood transfusion
These studies showed that antibody removal was much more efficient at 30 degrees C and 37 degrees C than at 18 degrees C or 25 degrees C