Digoxin elderly patients

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  • 3 percent overall, 26
  • 0 nanograms/mL); always interpret results in the clinical context
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  • 2022 Nov 26;46 (6):359-366
  • A beta-blocker or calcium
  • 1990 Sep;10 (3):479-92
  • There were no patients with ventricular arrhythmias or hypotension
  • [6, 11 Pharmacokinetics of Digoxin
  • From 2007 to 2014, there was a nearly 50% decrease in digoxin prescriptions dispensed among older adults

    heart failure), the prescribing of digoxin in older patients is inevitably going to increase

    7% (95% CI, 18

    Digoxin is a medication used to manage and treat heart failure and certain arrhythmias, and abortion

    Digoxin, commonly used to treat heart failure,1,2 has a narrow therapeutic range and is eliminated primarily by the kidney

    Estimated glomerular filtration rate is widely used to adjust

    13) Although we excluded patients with a

    27 Findings from the Digitalis Investigation Group recommended a lower plasma concentration compared with previous Objective: To resume the available literature about digoxin population pharmacokinetic studies in elderly patients

    The usual amount of digoxin injection that a 70 kg patient requires to achieve 8 to 12 mcg/kg peak body stores is 600 to 1000 mcg

    73 m 2 (risk of digoxin toxicity if plasma levels not measured) See also Prescribing in the elderly

    [ 58 ] Once differences in patient characteristics have been accounted for, it is unclear whether digoxin has a clear independent association with

    Digoxin is a cardiac glycoside that is widely prescribed for the treatment of congestive heart failure (CHF) and atrial fibrillation (AF)

    Digoxin may be adequate as monotherapy for ventricular rate control in patients with chronic AF, particularly in sedentary and elderly

    The main indications for digoxin usage include atrial fibrillation and heart failure; both these conditions are more prevalent in older patients

    Breast Feeding Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding

    Arch Intern Med 1991; 151:2194

    Further clinical studies are needed to confirm the pharmacokinetic parameters of digoxin in elderly patients with heart failure and/or atrial fibrillation

    Digoxin should be avoided or used with extreme caution in the very elderly or in patients with severe conduction abnormalities, acute coronary syndromes, or renal failure

    In this article, and unlike the other ones reviewed, the authors established as inclusion criteria patients with oral digoxin for more than 7 days and without serious hepatic or renal dysfunction

    Monitor creatinine clearance

    Therefore, providers are The trial population comprised primarily male patients, with only 22

    32 It is generally agreed that digoxin should be Background Digoxin is a cardiac glycoside that was introduced to cardiovascular medicine more than 200 years ago

    The data of 142 elderly patients and 448 samples were collected after repetitive oral digoxin

    macleod-glover@albertahealthservices

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