Recent data have clarified the teratogenic effect of high-dose fluconazole during the first trimester and provided reassuring cumulative data regarding its use at a single low dose in this key period
Oral terbinafine exposure was defined as filled prescriptions from 2 weeks before and throughout pregnancy
Objective: To examine the association between oral and topical terbinafine exposure in pregnancy and the risk of major malformations and spontaneous abortion
Although considered safe in pregnancy based on its classification, there are no reported cases of oral administration of terbinafine in humans during pregnancy or lactation
The Danish researchers drew from a registry of 1,650,649 pregnancies between 1997 and 2016, which included 891 pregnancies exposed to oral terbinafine, and 3,174 exposed to topical terbinafine
Consumer information about the medication TERBINAFINE CREAM - TOPICAL (Lamisil), includes side effects, drug interactions, recommended dosages, and storage information
In authors' opinion, combination of an oral agent and a topical formulation with different mechanisms of action can be tried in such cases e
• adults and children 12 years and over: • use the tip of the cap to break the seal and open the tube
Keep out of your mouth, nose, and eyes (may burn)
Contact with the face, eyes, or mucous membranes should be avoided
This website provides reliable, evidence-based, and accurate information about use of medicines in pregnancy, in the form of freely available patient information leaflets called 'Bumps' ('Best Use of Medicines in Pregnancy')
Terbinafine (Topical) monograph; Other brands Proper use of terbinafine
Oral and Topical Terbinafine for Fungal Infections in Pregnancy
doi: 10
Pronunciation (ter-BIN-uh-feen) Brand name(s) During pregnancy, this medication should be used only when clearly needed
HIV Infection With topical use: Preparations of terbinafine hydrochloride (maximum 1%) can be sold to the public for use in those over 16 years for external use for the treatment of tinea pedis as a cream in a pack containing maximum 15 g, or for the treatment of tinea pedis and cruris as a cream in a pack containing maximum 15 g, or for the treatment of tinea pedis, cruris, and corporis as a spray in a Mild-to-moderate potency topical corticosteroids are preferred, and usage should be limited to a short duration because large amounts of very potent topical steroids during pregnancy has been associated with low-birth-weight babies (Chi et al
Penetration into stratum corneum is similar following topical application of 1% cream or 1% solution
Learn about side effects, dosages, drug interactions, and more
During pregnancy, this Lamisil AT is not expected to harm an unborn baby
wash the affected skin with soap and water and dry completely before applying
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do
Because animal reproduction studies are not always predictive of human response, and because treatment of onychomycosis can be postponed until after pregnancy is completed, it is recommended that LAMISIL Tablets not be initiated during Is oral terbinafine safe in pregnancy? This nationwide cohort study found no increased risk of major malformations or spontaneous abortion among pregnancies exposed to oral or topical terbinafine
• wash the affected skin with soap and water Miconazole: is the preferred topical azole, compatible with breastfeeding
Pregnancy, breastfeeding and fertility Taking or using it with other medicines and herbal supplements Common questions Related conditions
on the bottom or sides of the foot: apply twice a day (morning and night) for 2 weeks or as Terbinafine side effects
Dosage form: gel
The topical treatment was officially approved by the FDA in 1993 and can be bought over the counter
Terbinafine is used to treat infections caused by a fungus
Terbinafine should be avoided during pregnancy as safety data are lacking and fungal nail infections do not require urgent treatment
The ability of many nontopical antifungals to penetrate the placenta and achieve measurable, often therapeutic Terbinafine topical has been assigned to pregnancy category B by the FDA
In recalcitrant/recurrent dermatophytosis, oral terbinafine is the safest choice
JAMA Dermatology 2020;56:375
Home Medicines A to Z Terbinafine Pregnancy, breastfeeding and fertility while taking or using terbinafine Brand names: Lamisil, Lamisil Once Terbinafine and pregnancy
Topical terbinafine has not been studied during breastfeeding
Manufacturer states that, unless the potential benefits outweigh any potential risks, topical terbinafine should not be administered during pregnancy
Monitor the infant for jaundice or other signs of liver toxicity, especially in younger, exclusively breastfed infants
Contact with the face, eyes, or mucous membranes should be avoided
This website provides reliable, evidence-based, and accurate information about use of medicines in pregnancy, in the form of freely available patient information leaflets called 'Bumps' ('Best Use of Medicines in Pregnancy')
Importance: Terbinafine is a commonly used antifungal agent, but safety data of its use in pregnancy are limited
Do not put on your nails or scalp
Apply enough terbinafine cream to cover the affected and surrounding skin areas and rub in gently
Oral and Topical Terbinafine for Fungal Infections in Pregnancy
1016/j
Denmark: Terbinafine is a commonly used antifungal agent, but safety data of its use in pregnancy are limited
Discuss the risks and benefits with your doctor
With topical use: Preparations of terbinafine hydrochloride (maximum 1%) can be sold to the public for use in those over 16 years for external use for the treatment of tinea pedis as a cream in a pack containing maximum 15 g, or for the treatment of tinea pedis and cruris as a cream in a pack containing maximum 15 g, or for the treatment of tinea pedis, cruris, and
Learn about side effects, dosages, drug interactions, and more
During pregnancy, this wash the affected skin with soap and water and dry completely before applying
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases
Because animal reproduction studies are not always predictive of human response, and because treatment of onychomycosis can be postponed until after pregnancy is completed, it is recommended that LAMISIL Tablets not be
• adults and children 12 years and over: • use the tip of the cap to break the seal and open the tube
5–1%: routinely used in US, UK and Canada for candidiasis of the nipple