Pomalyst velcade dexamethasone

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  • The most common side effects for treatment with Pomalyst and low-dose dexamethasone included neutropenia (low count of neutrophils, a type of white blood

    Return any unused Pomalyst to your doctor, or as directed

    Pomalidomide, cyclophosphamide, and dexamethasone for elderly patients with relapsed and refractory multiple myeloma: A study of the Korean Multiple Myeloma

    The median progression-free survival was 12

    Dexamethasone is a steroid

    However, conventional therapy is not curative and MM will ultimately relapse

    We analyzed the efficacy and safety of pomalidomide, cyclophosphamide, and dexamethasone (PomCiDex) in a real-world RRMM population

    The choice of pomalidomide is especially interesting owing to the synergistic antiproliferative activity of pomalidomide and dexamethasone in lenalidomide-resistant MM cells

    The Pomalyst-based combination also led to more “durable and deeper responses,” researchers noted, with about three times as many patients achieving a very good partial response or better (52

    As 1 example, in the ICARIA study, 47 evaluating isatuximab, pomalidomide, and dexamethasone vs pomalidomide and dexamethasone, 43% of patients required dose reductions of pomalidomide and 33% of patients required dose reductions in

    et al

    Pomalidomide plus low-dose dexamethasone is active and well tolerated in bortezomib and lenalidomide–refractory multiple myeloma Richardson PG, Oriol A, Beksac M, et al; OPTIMISMM trial investigators

    Dosing information

    Results from the phase 3 OPTIMISMM trial (NCT01734928) demonstrated that pomalidomide (P) in combination with bortezomib + dexamethasone (Vd) significantly

    Pomalidomide 4 mg was given on days 1 to 21 of 28-day cycles

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