Other anti-emetics are not routinely recommended due to side effects; Usual Adult Dose for Hypertension
Carcinogenic effects were not seen in 2 year studies in rats and mice with oral ondansetron doses up to 10 mg/kg per day and 30 mg/kg per day, respectively (approximately 4 and 6 times the maximum recommended human oral dose of 24 mg per day, based on body surface area)
The treatment duration should be for as long as clinically necessary
Comments: Do not use in patients less than 2 years old due to the risks of respiratory depression and serious cardiac
Initial dose: 5 mg orally once a day
Ordinarily a prompt diuresis ensues
Ondansetron was not mutagenic in standard tests for mutagenicity
Initial dose: 20 mg to 30 mg orally 2 times a day
Maintenance dose: 1 mg orally per day Maximum dose: 4 mg/day Comments: An increase to the target dose for most patients of 1 mg/day may be made after 3 days
The patients were randomly assigned to receive a single dose of oral ondansetron or a taste- and colour-matched placebo; oral rehydration was commenced