Concomitant use of AUBAGIO with other potentially hepatotoxic drugs may increase the risk of severe liver injury
• In psoriatic arthritis: leflunomide therapy is started with a loading dose of 100 mg once daily for 3 days
These effects can include excessive wind, bowel discomfort, loss of appetite, nausea (feeling sick) and diarrhoea
Leflunomide is indicated for the treatment of adult patients with: active rheumatoid arthritis as a 'disease-modifying antirheumatic drug' (DMARD)
Leflunomide is often used to treat rheumatoid arthritis alone or in
for complete
The chemical name for leflunomide is N-(4 ́-trifluoromethylphenyl)-5-methylisoxazole-4-carboxamide
Nausea, diarrhea, & weight loss Some people feel unwell with nausea when they take leflunomide
Leflunomide is indicated for the treatment of adult patients with: • active rheumatoid arthritis as a "disease-modifying antirheumatic drug" (DMARD), • active psoriatic arthritis
After this, most patients need a dose of: • For rheumatoid arthritis: 10 or 20 mg Leflunomide once daily, depending on the severity of the disease
Leflunomide (leflunomide tablets) should be used only by physicians who have fully familiarized themselves with the efficacy and safety profile of Leflunomide and who are experienced in the therapy of rheumatoid diseases
Resources from Manufacturer Full
Why are you being prescribed leflunomide? Leflunomide is one of a group of drugs that are called ‘disease-modifying’ drugs
Because of its effects on the immune system, leflunomide can reduce the inflammation that causes
Inhibits an enzyme required for pyrimidine synthesis; has antiproliferative and anti-inflammatory effects
A similar risk would be expected for teriflunomide because recommended doses of teriflunomide and leflunomide result in a similar range of plasma concentrations of teriflunomide