3% versus 5
Description and Brand Names
Fenofibrate is a fibrate that activates peroxisome proliferator activated receptor alpha (PPARα) to alter lipid metabolism and treat primary hypercholesterolemia, mixed
Fenofibrate, known as a peroxisome proliferator-activated receptor-α (PPAR-α) agonist, is a classic drug for treating hyperlipidemia
Special Populations
Find medical information for fenofibrate on epocrates online, including its dosing, contraindications, drug
Each capsule contains 67 mg, 134 mg or 200 mg of
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Fenofibric acid systemic is used in the treatment of: High Cholesterol
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This medicine has been available since 1975
Like other statins, it is an inhibitor of HMG-CoA reductase, the enzyme that catalyses the first step of cholesterol synthesis
[2] Each tablet contains 54 mg or 160 mg of fenofibrate
Fenofibrate should be used in
It is used to lower high levels of cholesterol and triglycerides in the blood and to increase HDL, the good cholesterol
112823 Da
Although both fibrates were well tolerated, the bioavailability of fenofibric acid and fenofibrate differed in the stomach (81% vs 69%, respectively; P = 0
These results show that orally administered fenofibric There are three agents of choice in the fibric acid drug class: fenofibric acid, fenofibrate, and gemfibrozil
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Mecha nism of Action
Canadian Brand Name
Fenofibrate requires once daily dosing and has a half life of 19-27 hours so its duration of action is long
Increase HDL cholesterol by about 20%
3
It works by increasing the natural substance (enzyme) that breaks down fats in the blood
7 hours for fenofibrate 145 mg and 160 mg respectively)