Management: Discontinue all drugs that may inhibit or interfere with catecholamine transport or uptake for at least 5 biological half-lives before iobenguane administration
Introduction Selective α 1 - and nonselective β-adrenergic blocking agent (β-blocker)
Forms and strengths, route of administration
Labetalol Dosage and Administration
Labetalol possesses significant intrinsic sympathomimetic activity
Labetalol is a beta-blocker that is used to treat hypertension ( high blood pressure )
Its alpha blockade action prevents epinephrine and
Care should therefore be taken in interpreting results from MIBG scintigraphy
During labetalol administration with a mean cumulative dose of 492 mg (ranging from 5 mg to 3960 mg), adverse events occurred in 18 patients (22
Labetalol is one of the most commonly used anti-hypertensives medications used for the treatment of hypertension during pregnancy
Peak concentrations are reached within 5 minutes of labetalol injection
25 mg/kg for an 80 kg patient) by slow intravenous injection over a 2
Labetalol hydrochloride tablets contain 100, 200, or 300 mg of labetalol HCl and are taken orally
2%
Since labetalol hydrochloride injection may be administered to patients already being treated with other medications, including other antihypertensive agents, careful monitoring of these patients is necessary to detect and treat promptly any undesired effect from concomitant administration
Jaundice or Hepatic Dysfunction (See WARNINGS
The plasma half-life of labetalol following oral administration is about 6 to 8 hours
25 mg/kg for an 80 kg patient) by slow intravenous injection Either of two methods of administration of labetalol hydrochloride injection may be used: a) repeated IV injection, or b) slow continuous infusion
9%), followed by bradycardia in 8 patients (10
As inj: 50 mg via bolus inj over at least 1 minute; if necessary, may be repeated at 5-minute intervals until a satisfactory response occurs
Se recomienda precaución si se administran ambos fármacos simultáneamente
25 mg/kg for an 80 kg patient) by slow intravenous Labetalol hydrochloride tablets, USP, for oral administration, contain 100 mg, 200 mg or 300 mg labetalol hydrochloride, USP