A fixed drug eruption (FDE) is an adverse skin reaction consisting of recurrent lesions at the same site after exposure to antibiotics, nonsteroidal anti
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In December 2020, the United States Food and Drug Administration granted emergency use authorization for the messenger RNA (mRNA)-1273 (Moderna) and
Most commonly, hypersensitivity to diphenhydramine manifests itself in patients receiving systemic drug after being sensitized to it by topical application
Reactions to radiocontrast media can be limited by pretreatment with prednisone, diphenhydramine, and either ephedrine or a histamine H2-receptor antagonist
Many of these patients have delayed forms of hypersensitivity, which typically begin more than six hours after the last administered dose and often after days of treatment
Fixed drug eruption (FDE), a localized variant of drug-induced dermatoses characterized by relapse in the same location, is a prototypic disorder mediated by excessive activation of effector memory T cells, which are resident in the lesional epidermis
The pattern of pigmentation may suggest a particular implicated drug; localised pigmentation on the face, lip, or genitalia may suggest a resolved fixed drug eruption
Identifying and avoiding the medicine that causes the reaction is often the first step in treating a
Diphenhydramine: Frequency not reported: Rash, pruritus, eczema, photosensitivity, urticaria, dyspnea, angioedema
If symptoms persist, consult your doctor
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the main causes of fixed drug eruption (FDE)
It is defined as a same-site recurrence with exposure to a particular medication
Fixed drug eruption
It is known that patients with such a reaction to tetracycline will cross-react to related drugs
NSAIDs are known to cause fixed drug eruptions, most probably through a hapten-type interaction
Fixed drug eruption due to norfloxacin and cross-reactivity with other quinolones
peculiar drug reaction