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Seladelpar, an investigational selective agonist of peroxisome proliferator–activated receptor-delta (PPAR-δ), significantly improves liver biomarkers of
Analysis
An in vitro enzyme inhibition study utilizing human liver microsomes showed that ziprasidone had little inhibitory effect on CYP1A2, CYP2C9, CYP2C19, CYP2D6 and
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There are 714 drugs known to interact with Geodon (ziprasidone), along with 18 disease interactions, and 4 alcohol/food interactions
Drink lots of noncaffeine liquids unless told to drink less liquid by
Are there any other medical conditions that would make someone ineligible for Geodon therapy? Talk to your doctor about other medical conditions before you take Geodon, such as a prolonged QT interval or arrhythmias, diabetes, dementia, seizures, low white blood cell count, high cholesterol, high or low blood
For schizophrenia: Adults—At first, 20 milligrams (mg) two times per
These withdrawal symptoms for me included really bad insomnia, which made it impossible to go to bed at all and caused hallucinations, flu like symptoms and more heart palpitations
The exact mechanism of action is unknown
It is created by eHealthMe based on reports from the FDA, and is updated regularly
If you get pregnant, tell your doctor right away
GEODON is indicated for the treatment of schizophrenia, as monotherapy for the acute treatment of bipolar manic or mixed episodes, and as an adjunct to lithium or valproate for the maintenance treatment of bipolar disorder
Store GEODON capsules at room temperature (59°F to 86°F or 15°C to 30°C)
studies using human liver microsomes and recombinant enzymes indicate that CYP3A4 is the major CYP contributing to the oxidative metabolism of ziprasidone
GEODON ® (ziprasidone HCl) studies utilizing human liver enzymes, ziprasidone is not a substrate for CYP1A2; smoking should therefore not have an effect on the pharmacokinetics of ziprasidone
They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc
3 The primary reductive pathway is catalyzed by aldehyde oxidase, while 2 other less prominent oxidative pathways are catalyzed by CYP3A4
Common side effects of Geodon include the following and should also be discussed with your doctor if they occur: Feeling unusually tired or sleepy
Abnormal muscle movements, including tremor, shuffling, and uncontrolled involuntary movements
Mania/psychosis: 40 to 80 mg PO BID; Acute agitation: 10-20mg IM q2-4h, 40mg max daily; Pediatric Dosing