10,11 Both the ROC-ALPS and ALIVE trials permitted dose reductions in lower-weight patients; however, higher cumulative bolus doses of amiodarone have not been studied in cardiac This is the first guideline update for SVT by ESC in 16 years
Treatment of pre-excited atrial fibrillation with intravenous digoxin, intravenous amiodarone, intravenous or oral β-blockers
com
S6-16 Limited data with amiodarone appeared to be promising, but a subsequent RCT involving 1073 patients found that administration of high-dose amiodarone led to a higher mortality rate, although a moderate
Although atrial flutter, atrial fibrillation, and multi-focal atrial tachycardia also arise from this area, in practice, SVT refers to atrioventricular nodal reentrant
Amiodarone is used to manage virtually all forms of supraventricular and ventricular tachycardia and has therefore become one of the most frequently used
For oral dosage form (tablets): For ventricular arrhythmias: Adults—At first, 800 to 1600 milligrams (mg) per day taken in divided doses
Indications and dose For amiodarone hydrochloride Treatment of arrhythmias, particularly when other drugs are ineffective or contra-indicated (including paroxysmal
DIAGNOSIS
087), during hours 0 to 6, when the largest number of patients were on blinded therapy
, within the first 24 hours after starting the amiodarone infusion)
May administer additional 150 mg following initial dose if VF/pVT persists after 3-5 minutes
g
Amiodarone hydrochloride is used in the treatment of arrhythmias, particularly when other drugs are ineffective or contraindicated
5-0
The loading dose of amiodarone can be followed by an infusion of 900 mg over 24 hours
5 mg/min for 18 hours or change to oral dosing
If jaundice appears, discontinue therapy
Can switch to a slow-release/extended release dose, which is available and preferred
These include: Dosage for ventricular tachycardia
4 to 16
Supraventricular tachycardia (SVT) is defined as an abnormally fast heartbeat
This article reviews the clinical features, diagnosis, and management of amiodarone-induced pulmonary and thyroid toxicity, based on the current evidence and guidelines
1 mg/kg IV bolus over 1 to 2 seconds
The efficacy of amiodarone was evaluated in 85 patients with supraventricular tachycardia (SVT) refractory to several antiarrhythmic agents (mean 3
Response to amiodarone treatment was considered excellent (no recurrence