A carbamate derivative used as an alcohol deterrent
May 14, 2020 — An off-label experiment in mice using disulfiram, which has been used to treat alcohol use disorder for more than 50 years, consistently normalized
Drowsiness, tiredness, headache, acne, and metallic/garlic-like taste in the mouth may occur as your body gets used to the medication
Disulfiram is a thiuram derivative which blocks the oxidation of alcohol at the acetaldehyde stage
Disulfiram works by interfering with the way your body breaks down
Disulfiram (brand name Antabuse) can be used if you're trying to achieve abstinence but are concerned you may relapse, or if you've had previous relapses
Initial dose: 500 mg orally once a day (this dose is generally continued for the first 1 to 2 weeks) Maintenance dose: 250 mg orally once a day (range: 125 mg to 500 mg once a day) Maximum dose: 500 mg once a day
The unpleasant reaction to alcohol acts as a deterrent that may help someone stop
Along with its needed effects, disulfiram may cause some unwanted effects
Common side effects of Disulfiram include: skin rash, acne, mild headache, tiredness, impotence, loss of interest in sex, and ; is not a complete list of side effects and other serious side effects or health problems may occur as a result of the use of this drug
Disulfiram works by interfering with the body’s digestion and
Methods: For this narrative review, a PubMed search was conducted for articles addressing in vivo studies of
Disulfiram Tablets, USP: 250 mg - White, capsule shaped tablets debossed “Σ 28” on one side and plain on the other side
glimepiride levels, risk of hypoglycemia, other adverse effects (hepatic metab
W
Each tablet for oral administration contains 250 mg or 500 mg disulfiram, USP and the following inactive ingredients: colloidal silicon All drugs may cause side effects