7 percent when
Extravasation and infiltration events are common occurrences with intravenous (IV) therapy and diagnostics ( )
While about two-thirds of all respondents limit promethazine concentration to 25 mg/mL, only about half of all respondents dilute the drug in 10 to 20 mL of saline
The best therapeutic agent for treatment of vasopressor extravasation is intradermal phentolamine
Promethazine is a medication used to manage and treat allergic conditions, nausea and vomiting, motion sickness, and sedation
Systemic heparin therapy remains the accepted treatment option for intraarteriolar
IV infiltration and extravasation involve the same process, they differ only by the type of fluid leaks into the extravascular space
Use safer alternatives that can be used for the same conditions IV promethazine treats, such as ondansetron (Zofran), prochlorperazine (Compazine), etc
Promethazine hydrochloride is metabolized in the liver, with the sulfoxides of promethazine and
1 Others distinguish infiltrations of non-vesicant solutions from extravasations with vesicant solutions
5-HT 3-receptor antagonists are reasonable second-line medications; the neurokinin receptor-1 antagonist, aprepitant, was effective in treatment of severe vomiting
Promethazine hydrochloride (10 -Phenothiazine-10-ethanamine, N,N, α-trimethyl-, monohydrochloride, (±)-) is a racemic compound and has the following structural
Although peripheral administration of vesicants may increase the risk of extravasation injuries, the time and resources required for
Each mL contains promethazine hydrochloride, either 25 mg or 50 mg, edetate disodium 0
0 to 5
Promethazine hydrochloride is metabolized in the liver, with the sulfoxides of promethazine and
If these complications occur, the provider will: Stop the IV flow
A second dose may be given 8–12 hours later if necessary
The skin around the IV site is blanche and cool
Call your doctor right away if you have slow, shallow, or trouble breathing