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    Objectives: Describe the mechanism of antibacterial action for erythromycin

    Erythromycin base, as crystals or powder, is slightly soluble in water, moderately soluble in ether, and readily soluble in alcohol or chloroform

    5 h, and low bioavailability

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    Erythromycin was discovered in 1952 among the metabolic products of the bacterium Streptomyces erythreus obtained from a soil sample

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    TIME/ACTION PROFILE (blood levels *) ROUTE ONSET PEAK Find information on Erythromycin (E-Mycin, Ery-Tab) in Davis's Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more

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    Wipe the tip of the ointment tube with a clean tissue to remove extra medication before recapping it

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    Erythromycin is contraindicated in patients taking terfenadine, astemizole, pimozide, or

    DESCRIPTION Erythromycin ophthalmic ointment, USP belongs to the macrolide group of antibiotics

    How Is This Medication Useful? Erythromycin is a macrolide antibiotic used

    Therapeutic Effects: Active against the following organisms: Staphylococcus aureus (methicillin and erythromycin-susceptible strains only), Streptococcus

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    If other diluents are used, solution is stable for 24 hr if refrigerated

    Each erythromycin delayed-release capsules, USP contains 250 mg of erythromycin base

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    PO (Children >1 mo): Base and ethylsuccinate– 30–50 mg/kg/day divided every 6–8 hr (max = 2 g/day as

    PO (Adults): Base, stearate– 250 mg every 6 hr, or 333 mg every 8 hr, or 500 mg every 12 hr

    250 mg of erythromycin base or stearate = 400 mg of erythromycin ethylsuccinate

    Erythromycin ophthalmic ointment, USP belongs to the macrolide group of antibiotics

    PO (Adults): Base, stearate– 250 mg every 6 hr, or 333 mg every 8 hr, or 500 mg every 12 hr

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    Erythrocin Lactobionate (Sterile Erythromycin Lactobionate, USP), is a soluble salt of erythromycin suitable for intravenous administration

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