The purpose was to (1) investigate the efficacy of allopurinol (standard dosage)
The purpose was to (1) investigate the efficacy of allopurinol (standard
The incidence rate of the composite CV event was higher in allopurinol
Benzbromarone increases urinary excretion of uric acid and the starting dose is 25–50 mg/d in adults, which should be adjusted to 75 or 100 mg/d according to the serum UA level
25% to 4
Based on the results of these searches, we selected ten medications to be included in our approved ULT list: allopurinol, febuxostat, topiroxostat, benzbromarone, dotinurad, lesinurad, probenecid, sulfinpyrazone, pegloticase, and rasburicase
Common uric acid-lowering therapies include allopurinol, benzbromarone, probenecid, and febuxostat
Rasburicase, a bacterial urate oxidase produced by genetic engineering, is indicated to prevent acute hyperuricemia induced by chemotherapy for hematological malignancies
We have
The reason for the withdrawal was the risk of fulminant hepatitis according to the information The uricosuric drugs include probenecid, sulfinpyrazone, and benzbromarone
Benzbromarone, sulfinpyrazone, probenecid and lesinurad (Figure S1) are among a class of gout therapeutics that lower sUA levels by inhibiting URAT1 and enhancing FEUA
Hanvivavadhanakul P, Akkasilpa S, Deesomchok U
The purpose was to (1) investigate the efficacy of allopurinol (standard dosage) compared with previous treatment with benzbromarone; and (2) investigate the combination therapy
5 out of 10 from a total of 87 ratings on Drugs
11 In a Benzbromarone is highly effective and well tolerated, and clinical trials as early as 1981 and as recently as April 2008 have suggested it is superior to both allopurinol, a non-uricosuric xanthine oxidase inhibitor, and probenecid, another uricosuric drug
Potential medications included allopurinol, febuxostat, pegloticase, rasburicase, probenecid, benzbromarone, sulphinpyrazone, losartan, fenofibrate and sodium–glucose linked transporter 2 inhibitors
Allopurinol 100mg, 300mg (tablet) First Choice: 1st Choice prophylaxis for gout Benzbromarone (tablet) Restricted: Unlicensed - High Risk Restricted - to prescribing by Consultant Rheumatologists for treatment of chronic gout in patients with mild to moderate renal impairment who are intolerant or have contraindications to, allopurinol
The drug is particularly useful in patients with chronic gouty arthritis and tophi, either refractory or allergic to probenecid, sulfinpyrazone, or allopurinol