Journal of the American Veterinary Medical Association 226, 1855–1863 [Google Scholar] Pharmacokinetic monitoring is the measurement of blood or plasma drug concentrations during therapy
Cyclosporine inhibits the action of the cells and proteins that signal to other cells to initialize an immune response
Cyclosporine
21
It works well by suppressing the immune system
A decrease in CD4 and CD8 cells was not seen in dogs receiving 20 mg/kg/day of cyclosporine for 56 days
Repeat administration every 4-8 weeks as needed in individual patients
Vomiting and diarrhea are seen in 30% of patients but are usually self-limiting within the first 7 to 10 days; administration with food or freezing the cyclosporine capsules may help decrease gastrointestinal upset
It is produced as a metabolite by the
The starting dose is usually 2