Pregnancy category of tetracycline

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  • 6 (95% CI 1
  • There are no controlled data in human pregnancy
  • Pregnancy Category N
  • -Examples: Phenytoin, Tetracycline
  • Not yet classified
  • plan to avoid unnecessary or prolonged exposure to sunlight and to
  • Drug pregnancy categories
  • Omadacycline
  • 6 Antiplatelet and Anticoagulants; 4
  • For all tetracyclines
  • Infant metronidazole serum levels may be close to or comparable to therapeutic levels

    Tetracycline has been assigned to pregnancy category D by the FDA

    Sulfonamides might pose a small risk of heart conditions, cleft lip or palate, and jaundice

    All agents were FDA Pregnancy Category B (amoxicillin, clindamycin, penicillin G, penicillin V potassium, and vancomycin) or C (chloramphenicol

    Animal

    If tetracyclines are taken during that time, they may cause the unborn infant's teeth to

    This information should not take the place of medical care and advice

    Although doxycycline is a semi-synthetic derivative of tetracycline, the available (albeit limited) evidence disassociates it from the permanent tooth

    Labeled as Pregnancy Category D, tetracyclines have proven teratogenicity in humans

    Tetracycline antibiotics

    Luckily, many commonly used antibiotics are considered safe for use during pregnancy

    Use of Tetracyclines During Pregnancy and Breastfeeding

    1 Antibiotics; 4

    2 AEDs

    Tetracycline use during tooth development (last half of pregnancy through age 8 years) can cause permanent discoloration of teeth Antianabolic action of the tetracyclines may cause an increase in BUN; in patients with significantly impaired renal function, higher serum levels of tetracycline may lead to azotemia, hyperphosphatemia and acidosis Background: Studies on potential maternal thyrotoxicity related to tetracycline antibiotics exposure during pregnancy are lacking

    Tetracycline has been associated with permanent tooth discoloration and bone development inhibition when given during the

    Tetracycline molecules comprise a linear fused tetracyclic nucleus (rings designated A, B, C and D) after use

    Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and

    * Effects on skeletal development of the embryo during the first-trimester have been documented in animal studies

    These are administered in different combinations depending upon the clinical condition

    Prophylaxis in high risk situations is also justified

    Repeated or long-term use of tetracycline during pregnancy may lead to a permanent discoloration of teeth in the baby because tetracycline accumulates in teeth and bones

    Describe if and how tetracycline impacts the growing baby? Also describe the FDA Pregnancy Category of tetracycline

    -Effective contraception (at least 2 reliable forms) is required during therapy and for 1 month after the last dose; local protocol should be consulted regarding contraception timing

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  • Pregnancy category of tetracycline
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