Infant metronidazole serum levels may be close to or comparable to therapeutic levels
Tetracycline has been assigned to pregnancy category D by the FDA
Sulfonamides might pose a small risk of heart conditions, cleft lip or palate, and jaundice
All agents were FDA Pregnancy Category B (amoxicillin, clindamycin, penicillin G, penicillin V potassium, and vancomycin) or C (chloramphenicol
Animal
If tetracyclines are taken during that time, they may cause the unborn infant's teeth to
This information should not take the place of medical care and advice
Although doxycycline is a semi-synthetic derivative of tetracycline, the available (albeit limited) evidence disassociates it from the permanent tooth
Labeled as Pregnancy Category D, tetracyclines have proven teratogenicity in humans
Tetracycline antibiotics
Luckily, many commonly used antibiotics are considered safe for use during pregnancy
Use of Tetracyclines During Pregnancy and Breastfeeding
1 Antibiotics; 4
2 AEDs
Tetracycline use during tooth development (last half of pregnancy through age 8 years) can cause permanent discoloration of teeth Antianabolic action of the tetracyclines may cause an increase in BUN; in patients with significantly impaired renal function, higher serum levels of tetracycline may lead to azotemia, hyperphosphatemia and acidosis Background: Studies on potential maternal thyrotoxicity related to tetracycline antibiotics exposure during pregnancy are lacking
Tetracycline has been associated with permanent tooth discoloration and bone development inhibition when given during the
Tetracycline molecules comprise a linear fused tetracyclic nucleus (rings designated A, B, C and D) after use
Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and
* Effects on skeletal development of the embryo during the first-trimester have been documented in animal studies
These are administered in different combinations depending upon the clinical condition
Prophylaxis in high risk situations is also justified
Repeated or long-term use of tetracycline during pregnancy may lead to a permanent discoloration of teeth in the baby because tetracycline accumulates in teeth and bones
Describe if and how tetracycline impacts the growing baby? Also describe the FDA Pregnancy Category of tetracycline
-Effective contraception (at least 2 reliable forms) is required during therapy and for 1 month after the last dose; local protocol should be consulted regarding contraception timing