Less than 5% of the maternal dose seems to be found in the breast-fed child [ 2 ]
DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects
Check with your doctor if you have breast swelling or soreness, unusual breast milk production, absent, missed, or irregular menstrual periods, stopping of menstrual bleeding, loss in sexual ability, desire, drive, or
Most studies have used metoclopramide in a dosage of 10 mg 2
It can increase milk supply by 66–100% within 2–5 days in total daily doses of 30–45 mg
This drug passes into breast milk and may have undesirable effects on a nursing infant
Ask your doctor about any risks
2020
- 80 mothers expressed breast milk for their infants (mean gestational age: 28 weeks) - Intervention group (n=38): metoclopramide PO 10 mg TDS - Milk production - Exclusion: all mothers <16 years of age, any mother who had an adverse reaction to either drug in the past or was taking other medication that might be contraindicated Administer from 10 mg to 15 mg metoclopramide hydrochloride orally up to q
Metoclopramide hydrochloride, USP, the active ingredient of metoclopramide tablets, USP is a dopamine-2 receptor antagonist
5 mg, Water for Injection, USP q
82 mg of metoclopramide hydrochloride)
Chemically, it is 4-amino-5-chloro-N- [2- (diethylamino)ethyl]-2-methoxy benzamide CLINICAL PHARMACOLOGY
periods stop) in girls and women C 14 H 22 ClN 3 O 2 •HCl•H 2 O
It should be inspected before use and discarded if either color or particulate is observed
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It also increases the efficacy of painkillers and migraine medication
Use of metoclopramide is contra-indicated in children aged under 1 year; Metoclopramide should only be prescribed for short-term use (up to 5 days); Recommended dose is 100–150 micrograms/kg (max
Metoclopramide hydrochloride is a white, crystalline, odorless substance, freely soluble in water
Metoclopramide can pass into breast milk and
Side effects may include sedation and movement disorders such as muscle rigidity and tardive dyskinesia
It is very soluble in water, freely soluble in alcohol, sparingly soluble in chloroform, practically insoluble in ether
Metoclopramide hydrochloride (metoclopramide monohydrochloride monohydrate) is a white or practically white, crystalline, odorless or practically odorless powder
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