Large doses of tramadol can cause a false positive for methadone or PCP
2 In this paper, we will review the existing literature on drug interactions principally between opioids used in the
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Substance Abuse & Addiction Guide Methadone Addiction: What to Know Medically Reviewed by Jennifer Casarella, MD on April 18, 2022 Written by Kendall K
Definitions for QT prolongation vary in the literature, but for men QTc >440 msec and for women QTc >470 msec are commonly used
Mechanism of Action Amitriptyline is in the tricyclic antidepressant (TCA) drug classification and acts by blocking the reuptake of both serotonin and norepinephrine neurotransmitters