Increased ammonia levels in your blood: High ammonia levels can seriously affect your mental activities, slow your alertness, make you feel tired, or cause Check with your doctor right away if you have the following symptoms: a fever, dark urine, headache, rash, stomach pain, swollen lymph glands in the neck, armpit, or groin, unusual tiredness, or yellow eyes or skin
loss of balance control
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
muscle tension or tightness
Hair loss is experienced by about one in nine people taking valproic acid
Although acute VPA intoxication frequently results in mild, self Hyperammonemia and hyperammonemic encephalopathy; measure ammonia level if unexplained lethargy and vomiting or changes in mental status, Ask your healthcare provider or pharmacist about possible side effects with Depakote Sprinkle Capsules
So, your risk of this side effect could be There are 51,553 people reported to have side effects when taking Depakote
If you or a loved one experiences these symptoms, call 911 or go to the nearest emergency room as soon as possible
Canadian Brand Name
High blood levels of ammonia have happened with Depakene (valproic acid capsules)
Sometimes, these brain problems have gone back to normal after Depakene Depakote does seem to be exceedingly toxic compared to other medications though
Ammonia (NH) is a colorless irritant gas with a pungent order that is readily soluble in water to generate ammonium (NH) ions
Haloperidol has received approval from the U
The plasma ammonia concentrations were significantly correlated with the percentage of free plasma carnitine in plasma (r = -0
Depakote is a prescription medication used in the treatment of bipolar disorder, epilepsy, and migraine prevention
In addition, there are no established guidelines of the next steps needed when a patient does develop this reaction
increased sweating
Gained a ton of weight very quickly, but it did solve the depression for me
High ammonia levels in your blood: feeling tired, vomiting, changes in mental status
Consult your doctor before taking Antabuse if pregnant or breastfeeding
Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain Most cases present asymptomatically with normal liver function tests
2007
What are Depakote’s side effects? Like most drugs, Depakote may
The common side effects of DEPAKOTE include: headache; loss of
joint or muscle pain
Divalproex sodium may cause some people to be agitated, irritable, or display other abnormal behaviors
Hair loss is experienced by about one in nine people taking valproic acid
Serious liver damage that can cause death, especially in children younger than 2 years old and patients with mitochondrial disorders
2)Complex Partial Seizures: Start at 10 to 15 mg/kg/day, increasing at 1 week intervals by 5 to 10 mg/kg/day
Depakote and Depakote ER can cause a high level of ammonia in your blood
These people tend to be male, 50-59 old, have been taking the drug for < 1 month, also take medication Neurontin, and
Symptoms of high ammonia levels in your blood include: Confusion and disorientation
Coma
Valproate-induced hepatotoxicity is a rare adverse event occurring in approximately 1 in 20,000 patients
Applies to: Depakote (divalproex sodium) and Topamax (topiramate) Using topiramate together with divalproex sodium may increase the risk of hyperammonemia, or elevated ammonia levels in the blood
Divalproex sodium is also used to treat the manic phase of bipolar disorder (manic-depressive illness) and helps prevent migraine headaches
Most of the time, this reaction has signs like fever, rash, or swollen glands with problems in body organs like the liver, kidney, blood, heart, muscles and joints, or lungs
These drug interactions can make your medication less effective or worsen side effects
Raja and Azzoni also note that mental status changes due to valproic acid are difficult to distinguish from worsening psychosis or mania or even from a therapeutic response
Food and