a
IV doses of furosemide are twice as potent as an oral formulation
The different modes of administration of bumetanide with dosages are the following: Subjects and study design
The bioavailability of torsemide is approximately 80%, which allows equivalency between oral and IV to 1 to 1, unlike furosemide (oral to IV is 2 to 1 )
Furosemide has been reported to have bioavailability ranging from 10–90% (average 50%), and a doubling of the furosemide dose is considered equivalent when changing from IV to oral
SC furosemide achieved equivalent natriuresis and diuresis compared with the IV formulation, both during the 0 to 8 hours period and the 0 to 24 hours 13 Patients were converted from their home loop diuretic to what was considered an equivalent IV dose, using a dose conversion of oral furosemide 40 mg to oral torsemide 20 mg and oral bumetanide 1 mg
5-2 hours
Current guidelines recommend 20 to 40 mg of IV furosemide for patients with AHF not receiving oral diuretics, or an equivalent or higher dose than the oral diuretics for those already taking it
Note: Based on bioavailability of oral Furosemide has an oral bioavailability of around 60%
Oral furosemide 40 mg is roughly equivalent to intravenous furosemide 20 mg
7 to 9 hours
However, it's important to remember the specific site of action for your board exams, that
Furosemide, USP is a white to slightly yellow, odorless, crystalline powder
Furosemide belongs to a group of medicines called loop diuretics (also known as water pills)
It
Use of intravenous furosemide rather than oral administration in acute decompensated congestive cardiac failure is universally recommended in international guidelines