Statin Name Approximate Percent Lowering of LDL* 20-25% 26-30% 31-35% 36-40% 41-50% 51-60% Atorvastatin (Lipitor) 10 mg 20 mg 40 mg 80 mg Nov 1, 2021 · The amount of LDL reduction classifies statins into low, moderate, or high intensity regimens
Atorvastatin and simvastatin are parts of a group of drugs called statins that revolutionized cholesterol management and heart disease prevention
Statins are often categorized by how much they lower LDL ("bad") cholesterol
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Simvastatin (Zocor) and atorvastatin (Lipitor) are two types of statins that your doctor may prescribe for you
However, of the 5023 switches from atorvastatin 20 mg to either branded or generic simvastatin, 2168 (43%) were to a lower therapeutic dose (15 switches to 5 mg, 220 to 10 mg, and 1933 to 20 mg Atorvastatin (Lipitor ®) Supplied: 10 mg, 20 mg, 40 mg, 80 mg
No Yes Continue treatment If intolerant of Atorvastatin, consider: Simvastatin, Pravastatin, Rosuvastatin, (Fluvastatin), Rosuvastatin 5mg non-daily dose (1-3 tablets weekly); Initiate at lowest dose
Simvastatin helps lower cholesterol production and reduce dyslipidemia-associated complications
Atorvastatin, branded as Lipitor by Pfizer, came to the market in 1996 and has since become one most widely used statin drugs
32% of reviewers reported a positive effect, while 49% reported a negative effect
The maximum price of simvastatin 40 mg is now up to six times cheaper than atorvastatin (£3
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Statins should not be restarted until Die AMK übernimmt keinerlei Gewähr für die inhaltliche Vollständigkeit und Aktualität dieser Informationen
More about Lipitor (atorvastatin) More about Zocor (simvastatin) Generic Status: Lower-cost generic is available
33% of reviewers reported a positive effect, while 53% reported a negative effect
Ezetimibe
Some people do not tolerate statins well and must use another medication to help 9% with pravastatin (Pravachol), 14
However, for some patients, it may take up to 2 months for symptom resolution
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29% of reviewers reported a positive effect, while 56% reported a negative effect
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Only a few cases of rhabdomyolysis occur per million people taking statins
These are a few of the main differences between Lipitor and Crestor: Side effects: Lipitor and Crestor may both cause muscle pain and certain digestive A meta-analysis published in the European Journal of Preventative Care found that atorvastatin was more effective than lovastatin and other statins for preventing heart attacks in those with or at risk of heart disease
Some formulations of this OTC medication have the same active ingredient as lovastatin
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Your doctor should discuss the risks and benefits of taking statins if they're offered to you
Comparative studies between atorvastatin and simvastatin with regard to LDL-C have shown that atorvastatin has superior milligram-equivalent efficacy compared with simvastatin over a dosage range Lipitor is a brand-name drug that contains the active drug atorvastatin, which is also available as a generic medication
Ezetimibe (Zetia) is a medication that's often prescribed in cases where a statin alone isn't enough
Comments: Following initiation and/or upon titration, lipid levels should be evaluated within 2 to 4 weeks and dosages adjusted accordingly
Lovastatin has an average rating of 6
30 Statins can be classified by the percentage that they can reduce LDL-C levels, referred to as the intensity, which may help in determining equivalent doses if switching between statins due to intolerance
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This confirmed that not all statins have the same effects on the human body, although they share the same molecular target
However, the doses between Crestor and simvastatin are not equivalent
Rosuvastatin has an average rating of 5
Learn dosage, side effects, and pregnancy safety information before taking this drug
Moderate-intensity statins can lower LDL cholesterol by approximately 30-50%
A service of the National Library of Medicine, National Institutes of Health
Simvastatin (Zocor, FloLipid) and atorvastatin (Lipitor) belong to a class of medications known as statins, which are considered to be first-choice medications for treating high cholesterol
However, of the 5023 switches from atorvastatin 20 mg to either branded or generic simvastatin, 2168 (43%) were to a lower therapeutic dose (15 switches to 5 mg
Comparing Atorvastatin vs Simvastatin Atorvastatin Simvastatin Prescription only Atorvastatin is effective at lowering cholesterol; however, its use may be limited by side
Atorvastatin (Lipitor) also has fewer drug interactions than simvastatin (Zocor) and can be used for
Simvastatin 80 mg is associated with an increased risk of myopathy
By lowering your cholesterol
Comparable reductions were not achieved with the maximum 80 mg doses of
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And you have been on both atorvastatin (Lipitor) and pravastatin (Pravachol)
Large quantities of grapefruit juice raise simvastatin and atorvastatin exposure
29% of reviewers reported a positive effect, while 56% reported a negative effect
Atorvastatin is a very effective clinical treatment option, but it may not work for everyone
46% of reviewers reported a positive effect, while 34% reported a negative effect
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24% of reviewers reported a positive effect, while 51% reported a negative Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis)
Atorvastatin competitively inhibits 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase
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29% of reviewers reported a positive effect, while 56% reported a negative effect
On the other hand, Lipitor is not for use in children younger than 7
Individualize dose based on goals of therapy and response