The 30+ fold glucocorticoid potency compared with hydrocortisone, absence of mineralocorticoid activity, and longer half life seem to make it a superior agent for perioperative supplementation for any level of stress
1 mg/kg is an effective adjunct in multimodal strategies to reduce postoperative pain and opioid consumption after surgery
We conclude that preoperative i
It has been used as an antiemetic in patients receiving
With the evidence presented, dexamethasone used in third molar surgeries is effective regardless of route of administration, dosage, and timing
A prospective, randomized, placebo-controlled study was conducted in 180 patients of either sex undergoing elective lower extremity and infraumbilical surgeries
A single intraoperative dose of dexamethasone has been shown to have significant benefits for alleviating postoperative nausea, vomiting, and pain, as well as
A total of 394 infants younger than 12 months, undergoing cardiac surgery with cardiopulmonary bypass were enrolled from Intraoperative hyperglycemia is a known phenomenon and intraoperative administration of dexamethasone may contribute or exaggerate this
compared Results
Br J Anaesth 118, 190–199 Dexamethasone has been shown to reduce acute pain after surgery, but there is uncertainty as to its effects on chronic postsurgical pain (CPSP)
examined the administration intraoperative intravenous dexamethasone in combination with 3 days of postoperative oral dexamethasone for total knee arthroplasty (TKA) patients in order to reduce postoperative pain, prevent postoperative nausea and vomiting, and improve early post operative ambulation
Four studies included additional study drugs, but groups were extracted to ensure the analgesic effect of dexamethasone was isolated (Badawy & Sakka, 2015; Kassim et al
Methods: This randomised, double-blind, controlled study was done by recruiting 150 non-diabetic adult patients of
Background: Dexamethasone prevents nausea and vomiting after anesthesia and may affect cancer proliferation
Conclusion In our trial of adults undergoing cardiac surgery, the use of intraoperative dexamethasone did not reduce the 30-day incidence of major adverse events compared with placebo
However, some studies have documented its association with hyperglycemia
In this randomized, double-blinded, placebo-controlled investigation, the effect of 2 standard intraoperative doses of dexamethasone (4 and 8 mg) on intraoperative and postoperative blood glucose concentrations was examined
The number of patients exposed to steroid therapy prior to surgery is increasing
Antibiotic dosing should be within 60 minutes of surgical incision 3
Methods: A total of 679 pancreaticoduodenectomies from a prospectively maintained database were analyzed