Drug interactions methotrexate and azithromycin

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  • Avoid combinations; the risk of the interaction outweighs the benefit
  • Major: Highly clinically significant
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    Carbamazepine, phenytoin, phenobarbital and primidone induce many cytochrome P450 (CYP) and glucuronyl transferase (GT Aciclovir Both Methotrexate and Aciclovir can increase the risk of nephrotoxicity

    Of the total drug interactions, 82 are major, 242 are moderate, and 21 are minor

    Applies to: methotrexate and azithromycin / trovafloxacin Medications like trovafloxacin may increase the blood levels of methotrexate in some patients

    Ritonavir, a strong cytochrome P450 (CYP) 3A4 inhibitor and a P-glycoprotein (P-gp) inhibitor, is coadministered with nirmatrelvir to increase the blood concentration of nirmatrelvir, thereby making it effective against SARS-CoV-2

    Alternatively, 500 mg PO x 1 dose on Day 1, followed by 250 mg PO qDay on Days 2-5

    Avoid combinations; the risk of the interaction outweighs the benefit

    Always consult your healthcare provider about how drug interactions should be Drug Interactions website or the University of Waterloo/University of Toronto drug interaction guide for specific dosing recommendations

    Major: Highly clinically significant

    It is created by eHealthMe based on reports from the FDA, and is These classifications are only a guideline

    Moderate Includes methotrexate, metoclopramide, naltrexone

    Always consult your healthcare provider before starting or stopping any medication

    Always consult your healthcare provider before starting or stopping any medication

    Always consult your healthcare provider before starting or stopping any medication

    Always consult your healthcare provider before starting or stopping any medication

    Always consult your healthcare provider before starting or stopping any medication

    If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines

    Avoid combinations; the risk of the interaction outweighs the benefit

    The relevance of a particular drug interaction to a specific individual is difficult to determine

    Like MTX, TMP-SMX is an inhibitor of folic acid metabolism and can cause bone marrow Cefdinir Interactions

    Always consult your healthcare provider before starting or stopping any medication

    The relevance of a particular drug interaction to a specific individual is difficult to determine

    The relevance of a particular drug interaction to a specific individual is difficult to determine

    This table provides examples It may have an interaction with other medications

    Tobi Podhaler (for Oral These classifications are only a guideline

    bone marrow suppression

    Always consult your healthcare provider before starting or stopping any medication

    Always consult your healthcare provider before starting or stopping any medication

    Moderate rifabutin, an antibiotic

    The relevance of a particular drug interaction to a specific individual is difficult to determine

    Always consult your healthcare provider before starting or stopping any medication

    The relevance of a particular drug interaction to a specific individual is difficult to determine

    There are 250 drugs known to interact with Wegovy (semaglutide), along with 6 disease interactions, and 2 alcohol/food interactions

    It received a lot of attention in 2020 as a potential treatment for COVID-19

    Always consult your healthcare provider before starting or stopping any medication

    Always consult your healthcare provider before starting or stopping any medication

    The phase IV clinical study analyzes what interactions people who take Methotrexate and Rocephin have

    Always consult your healthcare provider before starting or stopping any medication

    There is some concern with using methotrexate and azithromycin together, but overall, the combination is relatively safe to

    Published on November 28, 2022

    Use WebMD’s Drug Interaction Checker tool to find and identify potentially harmful and unsafe combinations of prescription medications by entering two or more drugs in

    Methotrexate's mechanism of action is due to its inhibition of enzymes responsible for nucleotide synthesis including dihydrofolate reductase, thymidylate

    Many interactions are theoretical or clinically trivial; however, some may have serious or life-threatening consequences

    Check for interactions against

    View interaction reports for Z-Pak (azithromycin) and the medicines listed below

    Both Methotrexate and Aciclovir can increase the risk of nephrotoxicity

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