Manufacturer advises monitor
Carbamazepine, phenytoin, phenobarbital and primidone induce many cytochrome P450 (CYP) and glucuronyl transferase (GT Aciclovir Both Methotrexate and Aciclovir can increase the risk of nephrotoxicity
Of the total drug interactions, 82 are major, 242 are moderate, and 21 are minor
Applies to: methotrexate and azithromycin / trovafloxacin Medications like trovafloxacin may increase the blood levels of methotrexate in some patients
Ritonavir, a strong cytochrome P450 (CYP) 3A4 inhibitor and a P-glycoprotein (P-gp) inhibitor, is coadministered with nirmatrelvir to increase the blood concentration of nirmatrelvir, thereby making it effective against SARS-CoV-2
Alternatively, 500 mg PO x 1 dose on Day 1, followed by 250 mg PO qDay on Days 2-5
Avoid combinations; the risk of the interaction outweighs the benefit
Always consult your healthcare provider about how drug interactions should be Drug Interactions website or the University of Waterloo/University of Toronto drug interaction guide for specific dosing recommendations
Major: Highly clinically significant
It is created by eHealthMe based on reports from the FDA, and is These classifications are only a guideline
Moderate Includes methotrexate, metoclopramide, naltrexone
Always consult your healthcare provider before starting or stopping any medication
Always consult your healthcare provider before starting or stopping any medication
Always consult your healthcare provider before starting or stopping any medication
Always consult your healthcare provider before starting or stopping any medication
Always consult your healthcare provider before starting or stopping any medication
If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines
Avoid combinations; the risk of the interaction outweighs the benefit
The relevance of a particular drug interaction to a specific individual is difficult to determine
Like MTX, TMP-SMX is an inhibitor of folic acid metabolism and can cause bone marrow Cefdinir Interactions
Always consult your healthcare provider before starting or stopping any medication
The relevance of a particular drug interaction to a specific individual is difficult to determine
The relevance of a particular drug interaction to a specific individual is difficult to determine
This table provides examples It may have an interaction with other medications
Tobi Podhaler (for Oral These classifications are only a guideline
bone marrow suppression
Always consult your healthcare provider before starting or stopping any medication
Always consult your healthcare provider before starting or stopping any medication
Moderate rifabutin, an antibiotic
The relevance of a particular drug interaction to a specific individual is difficult to determine
Always consult your healthcare provider before starting or stopping any medication
The relevance of a particular drug interaction to a specific individual is difficult to determine
There are 250 drugs known to interact with Wegovy (semaglutide), along with 6 disease interactions, and 2 alcohol/food interactions
It received a lot of attention in 2020 as a potential treatment for COVID-19
Always consult your healthcare provider before starting or stopping any medication
Always consult your healthcare provider before starting or stopping any medication
The phase IV clinical study analyzes what interactions people who take Methotrexate and Rocephin have
Always consult your healthcare provider before starting or stopping any medication
There is some concern with using methotrexate and azithromycin together, but overall, the combination is relatively safe to
Published on November 28, 2022
Use WebMD’s Drug Interaction Checker tool to find and identify potentially harmful and unsafe combinations of prescription medications by entering two or more drugs in
Methotrexate's mechanism of action is due to its inhibition of enzymes responsible for nucleotide synthesis including dihydrofolate reductase, thymidylate
Many interactions are theoretical or clinically trivial; however, some may have serious or life-threatening consequences
Check for interactions against
View interaction reports for Z-Pak (azithromycin) and the medicines listed below
Both Methotrexate and Aciclovir can increase the risk of nephrotoxicity